Effects of perindopril on cardiac sympathetic nerve activity in patients with congestive heart failure: comparison with enalapril

The production of aldosterone in the heart is suppressed by the angiotensin-converting enzyme (ACE) inhibitor perindopril in patients with congestive heart failure (CHF). Moreover, perindopril has been reported to have more cardioprotective effects than enalapril. Forty patients with CHF [left ventr...

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Bibliographic Details
Published in:European journal of nuclear medicine and molecular imaging 2005-08, Vol.32 (8), p.964-971
Main Authors: Kasama, Shu, Toyama, Takuji, Kumakura, Hisao, Takayama, Yoshiaki, Ichikawa, Shuichi, Suzuki, Tadashi, Kurabayashi, Masahiko
Format: Article
Language:English
Subjects:
3-Iodobenzylguanidine
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Angiotensin-Converting Enzyme Inhibitors - administration & dosage
Antihypertensive Agents
Enalapril - administration & dosage
Female
Heart Failure - diagnostic imaging
Heart Failure - drug therapy
Heart Ventricles - diagnostic imaging
Heart Ventricles - drug effects
Heart Ventricles - innervation
Humans
Male
Perindopril - administration & dosage
Radionuclide Imaging
Radiopharmaceuticals
Sympathetic Nervous System - diagnostic imaging
Sympathetic Nervous System - drug effects
Treatment Outcome
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Summary:The production of aldosterone in the heart is suppressed by the angiotensin-converting enzyme (ACE) inhibitor perindopril in patients with congestive heart failure (CHF). Moreover, perindopril has been reported to have more cardioprotective effects than enalapril. Forty patients with CHF [left ventricular ejection fraction (LVEF)
ISSN:1619-7070
1619-7089
DOI:10.1007/s00259-005-1786-z