Updating of normal levels of copper, zinc and selenium in serum of pregnant women

Selenium, copper and zinc status is important in pregnant women. The aim of this study was to establish updated normal ranges for these elements in serum of pregnant women from the Spanish region of Aragon, and to study variation in levels with respect to gestational period and maternal age. The stu...

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Published in:Journal of trace elements in medicine and biology 2007-01, Vol.21, p.49-52
Main Authors: Izquierdo Álvarez, Silvia, Castañón, Sandra García, Ruata, Maria Luisa Calvo, Aragüés, Elena Fuertes, Terraz, Pilar Bocos, Irazabal, Yolanda González, González, Elena García, Rodríguez, Beatriz García
Format: Article
Language:English
Subjects:
Adult
Copper
Copper - blood
Female
Humans
Pregnancy
Selenium
Selenium - blood
Serum
Zinc
Zinc - blood
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Summary:Selenium, copper and zinc status is important in pregnant women. The aim of this study was to establish updated normal ranges for these elements in serum of pregnant women from the Spanish region of Aragon, and to study variation in levels with respect to gestational period and maternal age. The study group consisted of 159 pregnant women who did not suffer from serious pathologies. These samples were classified into four gestational-period groups. Zn and Cu determinations were obtained by flame atomic absorption spectroscopy in a Perkin-Elmer 1100B apparatus, and Se was determined by electrothermal atomic absorption spectrometry with Zeeman correction, in a Perkin-Elmer 4110 ZL apparatus. The concentrations of Cu, Zn and Se averaged 73.61±43.67 μg/dL, 65.37±12.87 μg/dL and 99.59±21.74 μg/L, respectively. The Cu/Zn ratio increased from first trimester to the third trimester (2.07–3.49). There was no significant correlation between Zn and Se levels, but a significant correlation was found between Cu and Se levels ( p
ISSN:0946-672X
1878-3252
DOI:10.1016/j.jtemb.2007.09.023