Free radical scavenging activity of Achillea alexandri-regis extracts

The antioxidative potential of Achillea alexandri-regis has been studied by measuring the influence of herb extracts on hydroxyl and superoxide radicals' quantity in different in vitro systems. The ethyl acetate extract exhibited hydroxyl radical scavenging activity in all tested biological sys...

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Bibliographic Details
Published in:Fitoterapia 2005-09, Vol.76 (6), p.574-576
Main Authors: KUNDAKOVIC, T, MIMICA DUKIC, N, KOVACEVIC, N
Format: Article
Language:English
Subjects:
Achillea
Achillea alexandri-regis
Animals
Antioxidants - chemistry
Antioxidants - pharmacology
Antioxidative activity
Biological and medical sciences
Free Radical Scavengers - chemistry
Free Radical Scavengers - pharmacology
General pharmacology
Hydroxyl Radical - chemistry
Lipid Peroxidation - drug effects
Medical sciences
Mitochondria, Liver - drug effects
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Phytotherapy
Plant Extracts - chemistry
Plant Extracts - pharmacology
Radical scavenging activity
Rats
Superoxides - chemistry
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Summary:The antioxidative potential of Achillea alexandri-regis has been studied by measuring the influence of herb extracts on hydroxyl and superoxide radicals' quantity in different in vitro systems. The ethyl acetate extract exhibited hydroxyl radical scavenging activity in all tested biological system (liver homogenate, hemolyzed blood, serum and postmitochondrial liver fraction), whereas butanol extract reduced hydroxyl radicals significantly only in the postmitochondrial liver fraction. Both extracts showed superoxide radical scavenging effect only in hemolyzed blood.
ISSN:0367-326X
DOI:10.1016/j.fitote.2005.04.023