Construction of a small-molecule-integrated semisynthetic split intein for in vivo protein ligation

A new split intein-based protein ligation tool that is synthetically accessible and can be used for protein semisynthesis on the cell surface and potentially inside cells has been constructed.

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2007-01 (47), p.4995-4997
Main Authors: Ando, Tomomi, Tsukiji, Shinya, Tanaka, Tsutomu, Nagamune, Teruyuki
Format: Article
Language:English
Subjects:
Inteins
Models, Molecular
Molecular Sequence Data
Protein Splicing
Protein Structure, Tertiary
Proteins - chemistry
Proteins - genetics
Proteins - metabolism
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Description
Summary:A new split intein-based protein ligation tool that is synthetically accessible and can be used for protein semisynthesis on the cell surface and potentially inside cells has been constructed.
ISSN:1359-7345
1364-548X
DOI:10.1039/b712843f