Identification of Genes Involved in Healthy Aging and Longevity

:  Studies suggest that the region around microsatellite marker D4S1564 on chromosome 4 is in some way linked to longevity. As a part of the integrated European project Genetics of Healthy Aging (GeHA), we set out to investigate the genes found in this region using a proteomics approach. Here, we re...

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Bibliographic Details
Published in:Annals of the New York Academy of Sciences 2006-05, Vol.1067 (1), p.317-322
Main Authors: WEIBEL, JENS, DRÆBY SØRENSEN, MORTEN, KRISTENSEN, PETER
Format: Article
Language:English
Subjects:
Aging - genetics
antibodies
Chromosomes, Human, Pair 4
Cloning, Molecular
functional genomics
Gene Expression Profiling
Genes
Genetic Markers
genetics
Genomics - methods
Humans
Longevity - genetics
Microsatellite Repeats
Nucleic Acid Amplification Techniques
phage display
Proteomics - methods
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Summary::  Studies suggest that the region around microsatellite marker D4S1564 on chromosome 4 is in some way linked to longevity. As a part of the integrated European project Genetics of Healthy Aging (GeHA), we set out to investigate the genes found in this region using a proteomics approach. Here, we report the cloning of six candidate genes.
ISSN:0077-8923
1749-6632
DOI:10.1196/annals.1354.043