Mild Manganese(III) Acetate Catalyzed Allylic Oxidation:  Application to Simple and Complex Alkenes

Manganese(III) acetate catalyzed allylic oxidation of alkenes to the corresponding enones was investigated, showing excellent regioselectivity and chemoselectivity (functional group compatibility). Δ5-Steroids were transformed into bioactive Δ5-en-7-ones under a nitrogen atmosphere, whereas simple a...

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Bibliographic Details
Published in:Organic letters 2006-07, Vol.8 (14), p.3149-3151
Main Authors: Shing, Tony K. M, Yeung, Su, Pak L
Format: Article
Language:English
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Summary:Manganese(III) acetate catalyzed allylic oxidation of alkenes to the corresponding enones was investigated, showing excellent regioselectivity and chemoselectivity (functional group compatibility). Δ5-Steroids were transformed into bioactive Δ5-en-7-ones under a nitrogen atmosphere, whereas simple alkenes were converted into the corresponding enones under an oxygen atmosphere in good yields.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol0612298