Anti-oxidative and anti-inflammatory activities of two different species of a Chinese herb I-Tiao-Gung

The anti-oxidative and anti-inflammatory activities of two different species of traditional Chinese medicines that shared the same name have been studied. The extracts of Glycine radix have higher activities in free radical-scavenging activity determined with DPPH, reduction in hemoglobin-catalyzed...

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Bibliographic Details
Published in:Life sciences (1973) 2005-10, Vol.77 (22), p.2830-2839
Main Authors: Sun Pan, Bonnie, Kuo, Ying-Yu, Chen, Tsui-Yao, Liu, Yeuk-Chuen
Format: Article
Language:English
Subjects:
Anti-COX
Anti-inflammatory activities
Anti-Inflammatory Agents - metabolism
Anti-lipoxygenase
Anti-oxidation
Arachidonic Acid
Biphenyl Compounds
Chromatography, Gel
Chromatography, High Pressure Liquid
Cyclooxygenase 2 Inhibitors - metabolism
Drugs, Chinese Herbal - metabolism
Fabaceae - chemistry
Free Radical Scavengers - metabolism
Hydrazines
Isoflavones - isolation & purification
Isoflavones - metabolism
Lipoxygenase - metabolism
Magnetic Resonance Spectroscopy
Phenols - isolation & purification
Picrates
Taiwan
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Summary:The anti-oxidative and anti-inflammatory activities of two different species of traditional Chinese medicines that shared the same name have been studied. The extracts of Glycine radix have higher activities in free radical-scavenging activity determined with DPPH, reduction in hemoglobin-catalyzed lipid auto-oxidation and inhibition of the lipoxygenase (LOX) and cyclooxygenase (COX)-catalyzed arachidonate oxidation compared to the activities of extract of Flemingia. One of the significant bioactive constituents of Glycine radix has been isolated and identified as daidzein.
ISSN:0024-3205
1879-0631
DOI:10.1016/j.lfs.2005.05.027