Reduction of the incidence of neuroma formation by proximal epineural stripping: an experimental study in rats

The effect of proximal epineural stripping on neuroma formation was studied in the peroneal nerve stumps of the rat. After transection of the peroneal nerve, the epineurium of the proximal stump was stripped back by 6 to 8 mm and the nerve fascicles left uncovered in the study group. The transected...

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Bibliographic Details
Published in:Journal of hand surgery, British volume British volume, 2006-08, Vol.31 (4), p.450-452
Main Authors: Yildirim, A.M., Okur, M.İ., Özveren, F., Özercan, R.
Format: Article
Language:English
Subjects:
Animals
Disease Models, Animal
Neuroma - pathology
Neuroma - prevention & control
Neuroma - surgery
neuroma, proximal epineural stripping, epineurium, rat
Rats
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Summary:The effect of proximal epineural stripping on neuroma formation was studied in the peroneal nerve stumps of the rat. After transection of the peroneal nerve, the epineurium of the proximal stump was stripped back by 6 to 8 mm and the nerve fascicles left uncovered in the study group. The transected nerve was left untreated in the control group. All nerves were evaluated by light microscopy 6 months after the operation. Two neuromas occurred in 20 stumps after epineural stripping while 15 neuromas occurred in the control group. Based on histological data, we conclude that stripping of the epineurium may inhibit neuroma formation in the rat.
ISSN:0266-7681
1532-2211
DOI:10.1016/j.jhsb.2006.04.010