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Human papilloma virus is detectable by the Hybrid Capture 2 test in cervical smear samples from women over 40 years of age with high-grade squamous intraepithelial lesions
To establish that in Canterbury, New Zealand, women over the age of 40 with biopsy confirmed high grade squamous intraepithelial lesions (HSIL) have human papilloma virus (HPV) detectable by the Hybrid Capture 2 (HC2) test. Fifty‐two women with abnormal cytology under going colposcopy had HC2 perfor...
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Published in: | Australian & New Zealand journal of obstetrics & gynaecology 2005-10, Vol.45 (5), p.457-459 |
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container_title | Australian & New Zealand journal of obstetrics & gynaecology |
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creator | SYKES, Peter JENNINGS, Lance HARKER, Dianne BEYNON, Kirsten |
description | To establish that in Canterbury, New Zealand, women over the age of 40 with biopsy confirmed high grade squamous intraepithelial lesions (HSIL) have human papilloma virus (HPV) detectable by the Hybrid Capture 2 (HC2) test. Fifty‐two women with abnormal cytology under going colposcopy had HC2 performed. HPV status, cytology and histology were compared. HC2 was positive in 30/31 with grade 2 cervical intraepithelial neoplasia (CIN2) or worse, 5/6 with HPV changes or CIN1, and 10/15 with no demonstrated abnormality. |
doi_str_mv | 10.1111/j.1479-828X.2005.00455.x |
format | article |
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Fifty‐two women with abnormal cytology under going colposcopy had HC2 performed. HPV status, cytology and histology were compared. HC2 was positive in 30/31 with grade 2 cervical intraepithelial neoplasia (CIN2) or worse, 5/6 with HPV changes or CIN1, and 10/15 with no demonstrated abnormality.</description><identifier>ISSN: 0004-8666</identifier><identifier>EISSN: 1479-828X</identifier><identifier>DOI: 10.1111/j.1479-828X.2005.00455.x</identifier><identifier>PMID: 16171489</identifier><language>eng</language><publisher>550 Swanston Street (PO Box 378) Carlton South, Victoria 3053 Australia: Blackwell Science Pty</publisher><subject>Adult ; Age Factors ; Aged ; Carcinoma, Squamous Cell - pathology ; Carcinoma, Squamous Cell - virology ; Cervical Intraepithelial Neoplasia - pathology ; Cervical Intraepithelial Neoplasia - virology ; Cohort Studies ; Colposcopy - methods ; DNA Probes, HPV ; Female ; human papilloma virus ; Humans ; Hybrid Capture ; Incidence ; Middle Aged ; Neoplasm Staging ; New Zealand ; Papillomaviridae - isolation & purification ; Papillomavirus Infections - diagnosis ; Papillomavirus Infections - epidemiology ; Risk Assessment ; Sampling Studies ; Sensitivity and Specificity ; Uterine Cervical Neoplasms - epidemiology ; Uterine Cervical Neoplasms - pathology ; Uterine Cervical Neoplasms - virology ; Vaginal Smears</subject><ispartof>Australian & New Zealand journal of obstetrics & gynaecology, 2005-10, Vol.45 (5), p.457-459</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3495-ca8a0481d9fe8762824915131c6a81fcf546a52ccc38ce278343df973bbb10433</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16171489$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>SYKES, Peter</creatorcontrib><creatorcontrib>JENNINGS, Lance</creatorcontrib><creatorcontrib>HARKER, Dianne</creatorcontrib><creatorcontrib>BEYNON, Kirsten</creatorcontrib><title>Human papilloma virus is detectable by the Hybrid Capture 2 test in cervical smear samples from women over 40 years of age with high-grade squamous intraepithelial lesions</title><title>Australian & New Zealand journal of obstetrics & gynaecology</title><addtitle>Aust N Z J Obstet Gynaecol</addtitle><description>To establish that in Canterbury, New Zealand, women over the age of 40 with biopsy confirmed high grade squamous intraepithelial lesions (HSIL) have human papilloma virus (HPV) detectable by the Hybrid Capture 2 (HC2) test. Fifty‐two women with abnormal cytology under going colposcopy had HC2 performed. HPV status, cytology and histology were compared. 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JENNINGS, Lance ; HARKER, Dianne ; BEYNON, Kirsten</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3495-ca8a0481d9fe8762824915131c6a81fcf546a52ccc38ce278343df973bbb10433</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adult</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Carcinoma, Squamous Cell - pathology</topic><topic>Carcinoma, Squamous Cell - virology</topic><topic>Cervical Intraepithelial Neoplasia - pathology</topic><topic>Cervical Intraepithelial Neoplasia - virology</topic><topic>Cohort Studies</topic><topic>Colposcopy - methods</topic><topic>DNA Probes, HPV</topic><topic>Female</topic><topic>human papilloma virus</topic><topic>Humans</topic><topic>Hybrid Capture</topic><topic>Incidence</topic><topic>Middle Aged</topic><topic>Neoplasm Staging</topic><topic>New Zealand</topic><topic>Papillomaviridae - isolation & purification</topic><topic>Papillomavirus Infections - diagnosis</topic><topic>Papillomavirus Infections - epidemiology</topic><topic>Risk Assessment</topic><topic>Sampling Studies</topic><topic>Sensitivity and Specificity</topic><topic>Uterine Cervical Neoplasms - epidemiology</topic><topic>Uterine Cervical Neoplasms - pathology</topic><topic>Uterine Cervical Neoplasms - virology</topic><topic>Vaginal Smears</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SYKES, Peter</creatorcontrib><creatorcontrib>JENNINGS, Lance</creatorcontrib><creatorcontrib>HARKER, Dianne</creatorcontrib><creatorcontrib>BEYNON, Kirsten</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Australian & New Zealand journal of obstetrics & gynaecology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SYKES, Peter</au><au>JENNINGS, Lance</au><au>HARKER, Dianne</au><au>BEYNON, Kirsten</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Human papilloma virus is detectable by the Hybrid Capture 2 test in cervical smear samples from women over 40 years of age with high-grade squamous intraepithelial lesions</atitle><jtitle>Australian & New Zealand journal of obstetrics & gynaecology</jtitle><addtitle>Aust N Z J Obstet Gynaecol</addtitle><date>2005-10</date><risdate>2005</risdate><volume>45</volume><issue>5</issue><spage>457</spage><epage>459</epage><pages>457-459</pages><issn>0004-8666</issn><eissn>1479-828X</eissn><abstract>To establish that in Canterbury, New Zealand, women over the age of 40 with biopsy confirmed high grade squamous intraepithelial lesions (HSIL) have human papilloma virus (HPV) detectable by the Hybrid Capture 2 (HC2) test. Fifty‐two women with abnormal cytology under going colposcopy had HC2 performed. HPV status, cytology and histology were compared. HC2 was positive in 30/31 with grade 2 cervical intraepithelial neoplasia (CIN2) or worse, 5/6 with HPV changes or CIN1, and 10/15 with no demonstrated abnormality.</abstract><cop>550 Swanston Street (PO Box 378) Carlton South, Victoria 3053 Australia</cop><pub>Blackwell Science Pty</pub><pmid>16171489</pmid><doi>10.1111/j.1479-828X.2005.00455.x</doi><tpages>3</tpages></addata></record> |
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subjects | Adult Age Factors Aged Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - virology Cervical Intraepithelial Neoplasia - pathology Cervical Intraepithelial Neoplasia - virology Cohort Studies Colposcopy - methods DNA Probes, HPV Female human papilloma virus Humans Hybrid Capture Incidence Middle Aged Neoplasm Staging New Zealand Papillomaviridae - isolation & purification Papillomavirus Infections - diagnosis Papillomavirus Infections - epidemiology Risk Assessment Sampling Studies Sensitivity and Specificity Uterine Cervical Neoplasms - epidemiology Uterine Cervical Neoplasms - pathology Uterine Cervical Neoplasms - virology Vaginal Smears |
title | Human papilloma virus is detectable by the Hybrid Capture 2 test in cervical smear samples from women over 40 years of age with high-grade squamous intraepithelial lesions |
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