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Human papilloma virus is detectable by the Hybrid Capture 2 test in cervical smear samples from women over 40 years of age with high-grade squamous intraepithelial lesions

To establish that in Canterbury, New Zealand, women over the age of 40 with biopsy confirmed high grade squamous intraepithelial lesions (HSIL) have human papilloma virus (HPV) detectable by the Hybrid Capture 2 (HC2) test. Fifty‐two women with abnormal cytology under going colposcopy had HC2 perfor...

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Published in:Australian & New Zealand journal of obstetrics & gynaecology 2005-10, Vol.45 (5), p.457-459
Main Authors: SYKES, Peter, JENNINGS, Lance, HARKER, Dianne, BEYNON, Kirsten
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container_title Australian & New Zealand journal of obstetrics & gynaecology
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JENNINGS, Lance
HARKER, Dianne
BEYNON, Kirsten
description To establish that in Canterbury, New Zealand, women over the age of 40 with biopsy confirmed high grade squamous intraepithelial lesions (HSIL) have human papilloma virus (HPV) detectable by the Hybrid Capture 2 (HC2) test. Fifty‐two women with abnormal cytology under going colposcopy had HC2 performed. HPV status, cytology and histology were compared. HC2 was positive in 30/31 with grade 2 cervical intraepithelial neoplasia (CIN2) or worse, 5/6 with HPV changes or CIN1, and 10/15 with no demonstrated abnormality.
doi_str_mv 10.1111/j.1479-828X.2005.00455.x
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Fifty‐two women with abnormal cytology under going colposcopy had HC2 performed. HPV status, cytology and histology were compared. 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identifier ISSN: 0004-8666
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subjects Adult
Age Factors
Aged
Carcinoma, Squamous Cell - pathology
Carcinoma, Squamous Cell - virology
Cervical Intraepithelial Neoplasia - pathology
Cervical Intraepithelial Neoplasia - virology
Cohort Studies
Colposcopy - methods
DNA Probes, HPV
Female
human papilloma virus
Humans
Hybrid Capture
Incidence
Middle Aged
Neoplasm Staging
New Zealand
Papillomaviridae - isolation & purification
Papillomavirus Infections - diagnosis
Papillomavirus Infections - epidemiology
Risk Assessment
Sampling Studies
Sensitivity and Specificity
Uterine Cervical Neoplasms - epidemiology
Uterine Cervical Neoplasms - pathology
Uterine Cervical Neoplasms - virology
Vaginal Smears
title Human papilloma virus is detectable by the Hybrid Capture 2 test in cervical smear samples from women over 40 years of age with high-grade squamous intraepithelial lesions
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