A nondimensional normalization scheme for oxygen utilization data

The total oxygen required for gait (gross utilization) is a widely used indicator of locomotor efficiency. The standard scheme of mass normalization (dividing gross utilization by mass) is intended to eliminate confounding effects that arise from variations in age and size. Despite its prevalence, m...

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Bibliographic Details
Published in:Gait & posture 2006-08, Vol.24 (1), p.14-22
Main Authors: Schwartz, M.H., Koop, S.E., Bourke, J.L., Baker, R.
Format: Article
Language:English
Subjects:
Adolescent
Child
Child, Preschool
Gait
Gait - physiology
Humans
Infant
Normalization
Oxygen Consumption
Oxygen cost
Reference Values
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Summary:The total oxygen required for gait (gross utilization) is a widely used indicator of locomotor efficiency. The standard scheme of mass normalization (dividing gross utilization by mass) is intended to eliminate confounding effects that arise from variations in age and size. Despite its prevalence, mass normalization has been shown to be inadequate, as the normalized quantity retains a marked dependence on clinically relevant factors. The current study proposes a new scheme for normalizing oxygen utilization data. The new scheme, called net-nondimensional normalization, is based on the use of net oxygen utilization (gross − rest) and nondimensional gait variables. Measures of statistical significance are employed to demonstrate that net nondimensional normalization is superior to mass normalization. Net nondimensional oxygen utilization is shown to be largely independent of the relevant physiological and anatomical factors, and is therefore well suited for studies where an independent measure of gait efficiency is needed.
ISSN:0966-6362
1879-2219
DOI:10.1016/j.gaitpost.2005.06.014