Fusion and matrix protein gene sequence analysis of paramyxoviruses of type 1(PMV-1) isolated from pigeons in Slovenia

Paramyxoviruses of type 1 (PMV-l) isolated from pigeons were genetically analyzed. A part of the fusion and the matrix protein genes were amplified and sequenced, Typical amino acid sequences associated with virulence were determined at the fusion protein cleavage site in all PMV-1 isolates. All Slo...

Full description

Saved in:
Bibliographic Details
Published in:Virus genes 2005-12, Vol.31 (3), p.265-273
Main Authors: Barlic-Maganja, Darja, Krapez, Uros, Mankoc, Sara, Toplak, Ivan, Rojs, Olga Zorman
Format: Article
Language:English
Subjects:
Amino Acid Sequence
Animals
Base Sequence
Chickens - virology
Columbidae - virology
DNA, Viral - genetics
Genes, Viral
Molecular Sequence Data
Newcastle disease virus - genetics
Newcastle disease virus - isolation & purification
Newcastle disease virus - pathogenicity
Paramyxovirus
Phylogeny
Sequence Homology, Amino Acid
Slovenia
Viral Fusion Proteins - genetics
Viral Matrix Proteins - genetics
Virulence - genetics
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Paramyxoviruses of type 1 (PMV-l) isolated from pigeons were genetically analyzed. A part of the fusion and the matrix protein genes were amplified and sequenced, Typical amino acid sequences associated with virulence were determined at the fusion protein cleavage site in all PMV-1 isolates. All Slovene pigeon PMV-1 strains share high amino acid sequence similarity with other pigeon strains. In the phylogenetic tree, they are clustered together with pigeon PMV-1 isolates with moderate pathogenicity. Phylogenetic analysis obtained from the fusion and the matrix protein gene alignments showed the same branching order. Viruses circulating among pigeons were found to form quite unique lineage of virulent NDV strains.
ISSN:0920-8569
1572-994X
DOI:10.1007/s11262-005-3240-5