Hydrodynamic fabrication of polymeric barcoded strips as components for parallel bio-analysis and programmable microactuation

In this paper, we report a novel technique for the manufacture of polymeric barcoded strips having diverse characteristics such as biocatalyst-based sensing and pH-responsive actuation. The fabrication involves the use of both a microfluidic platform and in-situ photopolymerization. It is expected t...

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Bibliographic Details
Published in:Lab on a chip 2005-01, Vol.5 (10), p.1168-1172
Main Authors: Kim, SungRak, Oh, HyunJik, Baek, JuYeoul, Kim, HyugHan, Kim, WooSeung, Lee, SangHoon
Format: Article
Language:English
Subjects:
Antigens - chemistry
Catalysis
Dimethylpolysiloxanes
DNA - chemistry
Electrochemistry
Electrophoresis, Microchip - instrumentation
Electrophoresis, Microchip - methods
Enzymes - chemistry
Equipment Design
Hydrogen-Ion Concentration
Lactic Acid - chemistry
Light
Microchemistry
Microfluidic Analytical Techniques - methods
Microfluidics
Microscopy, Fluorescence
Models, Chemical
Oligonucleotide Array Sequence Analysis - methods
Photochemistry
Polymers - chemistry
Protein Array Analysis - methods
Time Factors
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Summary:In this paper, we report a novel technique for the manufacture of polymeric barcoded strips having diverse characteristics such as biocatalyst-based sensing and pH-responsive actuation. The fabrication involves the use of both a microfluidic platform and in-situ photopolymerization. It is expected that this method, which is a very simple, cost-effective, and environment-friendly means for mass production, will facilitate the stable immobilization of diverse biological substances such as enzymes, DNA, and antigens. Therefore, we fabricated an enzyme-immobilized barcoded strip for multiple bio-analysis. On the basis of this technology, we adopted different materials and thereby fabricated programmable microactuation components that are responsive to pH variation.
ISSN:1473-0197
1473-0189
DOI:10.1039/b506194f