Monoterpene lactones from the seeds of Nephelium lappaceum

Dichloromethane extracts of the seeds of Nephelium lappaceum afforded two new diastereomeric monoterpene lactones, 1 and 2, and the known butenolide siphonodin (3), as well as kaempferol 3-O-beta-D-glucopyranoside-7-O-alpha-L-rhamnopyranoside. Compounds 1 and 2 represent a new monoterpene skeleton,...

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Bibliographic Details
Published in:Journal of natural products (Washington, D.C.) D.C.), 2005-09, Vol.68 (9), p.1394-1396
Main Authors: Ragasa, C.Y, Luna, R.D. de, Cruz, W.C. Jr, Rideout, J.A
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - chemistry
Anti-Bacterial Agents - isolation & purification
Anti-Bacterial Agents - pharmacology
antibacterial properties
Antifungal Agents - chemistry
Antifungal Agents - isolation & purification
Antifungal Agents - pharmacology
antifungal properties
Aspergillus niger - drug effects
Bacillus subtilis - drug effects
Biological and medical sciences
Candida albicans - drug effects
chemical structure
Escherichia coli - drug effects
Fruit - chemistry
General pharmacology
lactones
Lactones - chemistry
Lactones - isolation & purification
Lactones - pharmacology
Medical sciences
medicinal plants
Microbial Sensitivity Tests
Molecular Structure
Monoterpenes - chemistry
Monoterpenes - isolation & purification
Monoterpenes - pharmacology
monoterpenoids
Nephelium lappaceum
Nuclear Magnetic Resonance, Biomolecular
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Philippines
phytochemicals
plant biochemistry
plant extracts
Plants, Medicinal - chemistry
Pseudomonas aeruginosa - drug effects
Sapindaceae - chemistry
seeds
Seeds - chemistry
spectral analysis
Staphylococcus aureus - drug effects
stereochemistry
Stereoisomerism
Trichophyton - drug effects
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Summary:Dichloromethane extracts of the seeds of Nephelium lappaceum afforded two new diastereomeric monoterpene lactones, 1 and 2, and the known butenolide siphonodin (3), as well as kaempferol 3-O-beta-D-glucopyranoside-7-O-alpha-L-rhamnopyranoside. Compounds 1 and 2 represent a new monoterpene skeleton, and their structures were elucidated by extensive 1D and 2D NMR spectral data interpretation. Antimicrobial testing was carried out on 1 and 2 against a panel of bacteria and fungi.
ISSN:0163-3864
1520-6025
DOI:10.1021/np0580053