Postexercise Nutrient Intake Enhances Leg Protein Balance in Early Postmenopausal Women

Background. We investigated the effect of nutrient administration after a session of resistance exercise on muscle protein kinetics in six healthy, early postmenopausal women, in a crossover design of random and double-blinded administration of protein and carbohydrate (PC) or placebo (NON). Methods...

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Bibliographic Details
Published in:The journals of gerontology. Series A, Biological sciences and medical sciences Biological sciences and medical sciences, 2005-09, Vol.60 (9), p.1212-1218
Main Authors: Holm, Lars, Esmarck, Birgitte, Suetta, Charlotte, Matsumoto, Keitaro, Doi, Tatsuya, Mizuno, Masao, Miller, Benjamin F., Kjaer, Michael
Format: Article
Language:English
Subjects:
Carbohydrates
Energy Metabolism - physiology
Exercise Test
Female
Gerontology
Humans
Leg - physiology
Legs
Middle Aged
Muscle, Skeletal - metabolism
Muscular system
Nutritional Physiological Phenomena - physiology
Postmenopause - physiology
Proteins
Proteins - metabolism
Reference Values
Women
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Summary:Background. We investigated the effect of nutrient administration after a session of resistance exercise on muscle protein kinetics in six healthy, early postmenopausal women, in a crossover design of random and double-blinded administration of protein and carbohydrate (PC) or placebo (NON). Methods. Fasted participants received a primed-constant infusion of L-[ring-2H5]-phenylalanine. After 90 minutes of rest, the participants performed leg-resistance exercises followed by the oral supplementation. During the following 4 hours, net protein balance (NB) and rate of disappearance and appearance of phenylalanine were calculated from arterial–venous blood samples and blood flow measurements. Results. NB was elevated (p
ISSN:1079-5006
1758-535X
DOI:10.1093/gerona/60.9.1212