Autoimmune phenomena following prostatectomy

Benign prostatic hypertrophy is the most common benign tumor in males, resulting in prostatectomy in 20-30% of men who live to the age of 80. There are no data on the association of prostatectomy with autoimmune phenomena in the English-language medical literature. To report our experience with thre...

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Bibliographic Details
Published in:The Israel Medical Association journal 2005-09, Vol.7 (9), p.575-577
Main Authors: Tweezer-Zaks, Nurit, Marai, Ibrahim, Livneh, Avi, Bank, Ilan, Langevitz, Pnina
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Autoimmune Diseases - drug therapy
Autoimmune Diseases - physiopathology
Humans
Male
Postoperative Complications - drug therapy
Postoperative Complications - physiopathology
Prostate
Prostatectomy
Prostatic Hyperplasia - surgery
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Summary:Benign prostatic hypertrophy is the most common benign tumor in males, resulting in prostatectomy in 20-30% of men who live to the age of 80. There are no data on the association of prostatectomy with autoimmune phenomena in the English-language medical literature. To report our experience with three patients who developed autoimmune disease following prostatectomy. Three patients presented awith autoimmune phenomenon soon after a prostectomy for BPH or prostatic carcinoma: one had clinically diagnosed temporal arteritis, one had leukocytoclastic vasculitis, and the third patient developed sensory Guillian-Barré syndrome following prostatectomy. In view of the temporal association between the removal of the prostate gland andthe autoimmune process, combined with previously known immunohistologic features of BPH, a cause-effect relationship probably exists.
ISSN:1565-1088