Biomolecular screening with novel organosilica microspheres

Organosilica microspheres synthesised via a novel surfactant-free emulsion-based method show applicability towards optical encoding, solid-phase synthesis and high-throughput screening of bound oligonucleotide and peptide sequences.

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2005-10 (38), p.4783-4785
Main Authors: Miller, Chris R, Vogel, Robert, Surawski, Peter P T, Corrie, Simon R, Rühmann, Andreas, Trau, Matt
Format: Article
Language:English
Subjects:
Microspheres
Oligonucleotides - chemistry
Optics and Photonics
Organosilicon Compounds - chemical synthesis
Organosilicon Compounds - chemistry
Particle Size
Peptides - chemistry
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Description
Summary:Organosilica microspheres synthesised via a novel surfactant-free emulsion-based method show applicability towards optical encoding, solid-phase synthesis and high-throughput screening of bound oligonucleotide and peptide sequences.
ISSN:1359-7345
1364-548X
DOI:10.1039/b509503d