Ghrelin, leptin and IGF-I levels in breast-fed and formula-fed infants in the first years of life

To establish ghrelin, leptin and IGF-I serum levels in breastfed (BF) and formula-fed (FF) infants during the first period of life. A cross-sectional study was conducted on fasting blood venous samples obtained from exclusively BF (n=106) and FF (n=100) infants to measure total ghrelin (RIA test), l...

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Bibliographic Details
Published in:Acta pædiatrica (Oslo) 2005-05, Vol.94 (5), p.531-537
Main Authors: Savino, Francesco, Fissore, Maria F, Grassino, Erica C, Nanni, Giuliana E, Oggero, Roberto, Silvestro, Leandra
Format: Article
Language:English
Subjects:
Anthropometry
Bottle Feeding
Breast Feeding
Cross-Sectional Studies
Female
Ghrelin
Humans
Infant
Infant, Newborn
Insulin-Like Growth Factor I - metabolism
Leptin - blood
Male
Peptide Hormones - blood
Regression Analysis
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Summary:To establish ghrelin, leptin and IGF-I serum levels in breastfed (BF) and formula-fed (FF) infants during the first period of life. A cross-sectional study was conducted on fasting blood venous samples obtained from exclusively BF (n=106) and FF (n=100) infants to measure total ghrelin (RIA test), leptin (RIA test) and IGF-I (chemiluminescence). Anthropometrical measurements of weight, length and cranial circumference were performed. During the first 4 mo of life, FF infants compared to BF ones showed higher ghrelin levels (2654.86 vs 2132.96 pg/ml; p
ISSN:0803-5253
DOI:10.1080/08035250510027642