Prevalence, clinical profile, and significance of left ventricular remodeling in the end-stage phase of hypertrophic cardiomyopathy

End stage (ES) is a recognized part of the hypertrophic cardiomyopathy (HCM) disease spectrum. Frequency, clinical profile and course, and treatment strategies in these patients remain incompletely defined. Three HCM cohorts comprised 1259 patients, including 44 (3.5%) characterized as ES with systo...

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Published in:Circulation (New York, N.Y.) N.Y.), 2006-07, Vol.114 (3), p.216-225
Main Authors: HARRIS, Kevin M, SPIRITO, Paolo, MARON, Martin S, ZENOVICH, Andrey G, FORMISANO, Francesco, LESSER, John R, MACKEY-BOJACK, Shannon, MANNING, Warren J, UDELSON, James E, MARON, Barry J
Format: Article
Language:English
Subjects:
Adolescent
Adult
Biological and medical sciences
Blood and lymphatic vessels
Blood. Blood coagulation. Reticuloendothelial system
Cardiology. Vascular system
Cardiomyopathy, Hypertrophic - diagnostic imaging
Cardiomyopathy, Hypertrophic - epidemiology
Cardiomyopathy, Hypertrophic - pathology
Cardiomyopathy, Hypertrophic - physiopathology
Child
Cohort Studies
Coronary heart disease
Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous
Echocardiography
Female
Follow-Up Studies
Heart
Humans
Magnetic Resonance Imaging
Male
Medical sciences
Pharmacology. Drug treatments
Prevalence
Retrospective Studies
Time Factors
United States - epidemiology
Ventricular Remodeling - physiology
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Summary:End stage (ES) is a recognized part of the hypertrophic cardiomyopathy (HCM) disease spectrum. Frequency, clinical profile and course, and treatment strategies in these patients remain incompletely defined. Three HCM cohorts comprised 1259 patients, including 44 (3.5%) characterized as ES with systolic dysfunction (ejection fraction
ISSN:0009-7322
1524-4539
DOI:10.1161/CIRCULATIONAHA.105.583500