Oestrogen and progesterone receptors in primary mucinous carcinoma of skin

SUMMARY A 74‐year‐old man presented with a recurrent indolent growth in the left axilla. Fine‐needle aspiration cytology and histopathological examination showed a picture of mucinous adenocarcinoma. Clinical examination and systemic investigations failed to detect any primary lesion elsewhere and h...

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Bibliographic Details
Published in:Australasian journal of dermatology 2005-11, Vol.46 (4), p.246-249
Main Authors: Kwatra, Kanwardeep S, Prabhakar, Baldev R, Jain, Satish
Format: Article
Language:English
Subjects:
adenocarcinoma
Adenocarcinoma, Mucinous - metabolism
Adenocarcinoma, Mucinous - pathology
adnexal
Aged
Axilla - pathology
Biological and medical sciences
cutaneous
Dermatology
eccrine
hormone receptors
Humans
Immunohistochemistry - methods
Male
Medical sciences
Receptors, Estrogen - analysis
Receptors, Progesterone - analysis
Skin Neoplasms - metabolism
Skin Neoplasms - pathology
sweat gland
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Summary:SUMMARY A 74‐year‐old man presented with a recurrent indolent growth in the left axilla. Fine‐needle aspiration cytology and histopathological examination showed a picture of mucinous adenocarcinoma. Clinical examination and systemic investigations failed to detect any primary lesion elsewhere and hence, a diagnosis of primary mucinous carcinoma of the skin was made. This tumour shows histological resemblance to mucinous carcinoma of breast. We also demonstrated expression of oestrogen and progesterone receptors in this tumour. This observation suggests that there is a potential of using antioestrogenic therapy in patients with primary cutaneous mucinous carcinoma, especially because of its high rate of local recurrence.
ISSN:0004-8380
1440-0960
DOI:10.1111/j.1440-0960.2005.00193.x