Coronary surgery in dialysis-dependent patients with end stage renal failure

The number of patients with dialysis-dependent end stage renal failure (ESRF) and coronary heart disease (CAD) has increased in recent years. Coronary artery bypass grafting (CABG) has become the standard treatment for CAD in this patient group, but is still considered as a risk procedure due to inc...

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Bibliographic Details
Published in:Clinical research in cardiology 2005-10, Vol.94 (10), p.679-683
Main Authors: Tugtekin, S M, Alexiou, K, Georgi, Ch, Kappert, U, Knaut, M, Matschke, K
Format: Article
Language:English
Subjects:
Aged
Bypass
Cardiovascular disease
Cardiovascular diseases
Coronary artery
Coronary Artery Bypass - mortality
Coronary artery disease
Dialysis
Extracorporeal Circulation - mortality
Female
Germany - epidemiology
Heart diseases
Heart surgery
Hemodialysis
Humans
Kidney Failure, Chronic - mortality
Kidney Failure, Chronic - rehabilitation
Male
Morbidity
Mortality
Patients
Prevalence
Renal Dialysis - mortality
Renal failure
Renal function
Retrospective Studies
Risk Assessment - methods
Risk Factors
Treatment Outcome
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Summary:The number of patients with dialysis-dependent end stage renal failure (ESRF) and coronary heart disease (CAD) has increased in recent years. Coronary artery bypass grafting (CABG) has become the standard treatment for CAD in this patient group, but is still considered as a risk procedure due to increased mortality and morbidity. In a retrospective study we analyzed our clinical results of isolated CABG in 40 dialysis-dependent patients with ESRF (5 female and 35 male, mean age 65+/-8.4 years) and the use of extracorporeal circulation. The perioperative control group comprised 51 patients (10 female and 41 male, mean age 67+/-7.3 years) with normal renal function and isolated CABG. Demographic and preoperative data were comparable in both groups. Hospital mortality was 2.5% in patients with ESRF and 0% in patients with normal renal function. Morbidity was comparable in both groups. The mean number of grafts was 3.1+/-0.9 in the dialysis group and 2.9+/-0.8 in the control group. In the follow-up of the dialysis group (34+/-23 months) 8 patients died. CABG in patients with dialysis-dependent ESRF can be performed with good clinical results and morbidity comparable to patients with normal renal function.
ISSN:0300-5860
1861-0684
1435-1285
1861-0692
DOI:10.1007/s00392-005-0286-2