In vitro evaluation of stent patency and in-stent stenoses in 10 metallic stents using MR angiography

In vitro study to investigate the suitability of contrast enhanced magnetic resonance angiography (CEMRA) for determination of stent patency and grading of in-stent stenoses in 10 metallic stents. The Acculink carotid, DynaLink, Easy Wallstent, JostentSelfX XF, Luminexx, Omnilink, sinus-SuperFlex, S...

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Bibliographic Details
Published in:British journal of radiology 2006-08, Vol.79 (944), p.636-643
Main Authors: HAMER, O. W, BORISCH, I, PAETZEL, C, NITZ, W. R, SEITZ, J, FEUERBACH, S, ZORGER, N
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cardiovascular system
Graft Occlusion, Vascular - diagnosis
Humans
Investigative techniques, diagnostic techniques (general aspects)
Magnetic Resonance Angiography - standards
Medical sciences
Phantoms, Imaging
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Sensitivity and Specificity
Stents - standards
Vascular Patency
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Summary:In vitro study to investigate the suitability of contrast enhanced magnetic resonance angiography (CEMRA) for determination of stent patency and grading of in-stent stenoses in 10 metallic stents. The Acculink carotid, DynaLink, Easy Wallstent, JostentSelfX XF, Luminexx, Omnilink, sinus-SuperFlex, SMART, Symphony and ZA stent were separately placed in a vascular phantom. Dedicated stenoses inside the stents generated a concentric lumen narrowing of 50%. CEMRA was performed for each stent. Signal loss inside the stents and artificial lumen narrowing were assessed objectively using the evaluation software of the MR imager. Moreover, three blinded observers determined visibility of stent patency and in-stent stenoses subjectively on a 3-point scale and graded in-stent stenoses. Loss of signal intensity within the stent lumen ranged between 90% (Wallstent) and 5% (ZA), artificial lumen narrowing between 56% (Symphony) and 22% (ZA). For the Symphony and Wallstent, visibility of patency and in-stent stenoses was impaired and the observers' grading exaggerated the degree of stenoses (by 23% and 33%, respectively). For the remainder of stents, patency and stenoses were visible and stenoses were graded accurately (less than 10% discrepancy from reference standard). In this in vitro study, eight of 10 stents presented with MRI characteristics which enabled determination of stent patency and accurate grading of clinically relevant in-stent stenoses.
ISSN:0007-1285
1748-880X
DOI:10.1259/bjr/57301879