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Curative radiotherapy for early cancers of the lip, buccal mucosa, and nose--a simple interstitial brachytherapy technique employing angiocatheters as carriers for Iridium-192 wire implants

To evaluate treatment outcomes following interstitial brachytherapy for cancers of the lip, buccal mucosa, or nose. Retrospective study. Regional hospital, Hong Kong. A cohort of 13 patients treated uniformly by a simple interstitial brachytherapy technique employing plastic angiocatheters as carrie...

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Bibliographic Details
Published in:Hong Kong medical journal = Xianggang yi xue za zhi 2005-10, Vol.11 (5), p.351-359
Main Authors: Ngan, R K C, Wong, R K Y, Tang, F N F, Tang, D L C
Format: Article
Language:English
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Summary:To evaluate treatment outcomes following interstitial brachytherapy for cancers of the lip, buccal mucosa, or nose. Retrospective study. Regional hospital, Hong Kong. A cohort of 13 patients treated uniformly by a simple interstitial brachytherapy technique employing plastic angiocatheters as carriers for Iridium-192 wires: all but one patient had T1 or T2 tumours and all but one had N0 disease. Local and loco-regional control rates. Six of the 13 patients received external radiotherapy prior to interstitial brachytherapy. A median brachytherapy dose of 70 Gy was delivered to those treated with brachytherapy alone, while 35 Gy was delivered after a median external radiotherapy dose of 50 Gy to those receiving combined treatment. The 3-year actuarial local control rate was 75%. No significant late complications were observed. Employing a simple brachytherapy technique using angiocatheters and Iridium-192 wires, in conjunction with external radiotherapy when appropriate, produces good outcomes for patients with early lip, nasal vestibule, and buccal mucosa cancers.
ISSN:1024-2708
2226-8707