The chlamydial developmental cycle

Intracellular parasitism by bacterial pathogens is a complex, multi-factorial process that has been exploited successfully by a wide variety of organisms. Members of the Order Chlamydiales are obligate intracellular bacteria that are transmitted as metabolically inactive particles and must different...

Full description

Saved in:
Bibliographic Details
Published in:FEMS microbiology reviews 2005-11, Vol.29 (5), p.949-959
Main Authors: AbdelRahman, Yasser M., Belland, Robert J.
Format: Article
Language:English
Subjects:
Animals
Bacteria
Bacterial Proteins - genetics
Bacterial Proteins - metabolism
Bacteriology
Biological and medical sciences
Cell differentiation
Chlamydia
Chlamydia - genetics
Chlamydia - growth & development
Chlamydia - metabolism
Chlamydia - pathogenicity
Chlamydiales
Deoxyribonucleic acid
DNA
DNA chips
DNA microarrays
Fundamental and applied biological sciences. Psychology
Gene expression
Gene Expression Regulation, Bacterial
Gene sequencing
Genomes
HeLa Cells
Humans
Intracellular
Life cycles
Microarray analysis
Microbiology
Miscellaneous
Nucleotide sequence
Oligonucleotide Array Sequence Analysis
Parasitism
Polymerase Chain Reaction
Prokaryotic development
Transcription
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Intracellular parasitism by bacterial pathogens is a complex, multi-factorial process that has been exploited successfully by a wide variety of organisms. Members of the Order Chlamydiales are obligate intracellular bacteria that are transmitted as metabolically inactive particles and must differentiate, replicate, and re-differentiate within the host cell to carry out their life cycle. Understanding the developmental cycle has been greatly advanced by the availability of complete genome sequences, DNA microarrays, and advanced cell biology techniques. Measuring transcriptional changes throughout the cycle has allowed investigators to determine the nature of the temporal gene expression changes required for bacterial growth and development.
ISSN:0168-6445
1574-6976
DOI:10.1016/j.femsre.2005.03.002