Synthesis of IL-2 mRNA in cells of rat hypothalamic structures after injection of short peptides

In situ hybridization on paraffin sections of the rat brain showed that synthetic peptides Vilon, Epithalon, and Cortagen modulated the expression of IL-2 gene in vivo in cells of some hypothalamic structures depending on the terms and routes of administration.

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2005-06, Vol.139 (6), p.718-720
Main Authors: Kazakova, T B, Barabanova, S V, Novikova, N S, Glushikhina, M S, Khavinson, V Kh, Malinin, V V, Korneva, E A
Format: Article
Language:English
Subjects:
Administration, Inhalation
Animals
Hypothalamus - cytology
Hypothalamus - metabolism
Immunohistochemistry
In Situ Hybridization
Injections, Intramuscular
Interleukin-2 - biosynthesis
Interleukin-2 - genetics
Male
Oligopeptides - administration & dosage
Oligopeptides - chemistry
Oligopeptides - pharmacology
Rats
Rats, Sprague-Dawley
RNA, Messenger - biosynthesis
RNA, Messenger - genetics
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Description
Summary:In situ hybridization on paraffin sections of the rat brain showed that synthetic peptides Vilon, Epithalon, and Cortagen modulated the expression of IL-2 gene in vivo in cells of some hypothalamic structures depending on the terms and routes of administration.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-005-0388-x