Concurrence of glioma and multiple sclerosis

A 29-year-old Caucasian female diagnosed with multiple sclerosis (MS) for seven years, presented with a history of headaches and a single episode of new onset seizures. Her physical examination was unremarkable and she was placed on anti-seizure medications. A computed tomography (CT) scan showed a...

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Bibliographic Details
Published in:Canadian journal of neurological sciences 2005-08, Vol.32 (3), p.349-351
Main Authors: Khan, Shah-Naz Hayat, Buwembo, Joseph E., Li, Q.
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Biopsy
Brain Neoplasms - complications
Brain Neoplasms - diagnostic imaging
Brain Neoplasms - pathology
Female
Glioma - complications
Glioma - diagnostic imaging
Glioma - pathology
Humans
Immunomodulators
Magnetic Resonance Imaging
Medical sciences
Multiple Sclerosis - complications
Multiple Sclerosis - diagnostic imaging
Multiple Sclerosis - pathology
Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis
Neuroimaging Highlight
Neurology
Pharmacology. Drug treatments
Tomography, X-Ray Computed
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Summary:A 29-year-old Caucasian female diagnosed with multiple sclerosis (MS) for seven years, presented with a history of headaches and a single episode of new onset seizures. Her physical examination was unremarkable and she was placed on anti-seizure medications. A computed tomography (CT) scan showed a right frontal brain lesion causing minimal mass effect (Figure 1). Magnetic resonance imaging (MRI) revealed a large nonenhancing space occupying lesion in the right frontal lobe, in addition to numerous smaller lesions which were characteristic of MS plaques (Figures 2 & 3). The large lesion was causing mass effect with right to left midline shift (Figures 2, 3A & B). Given the patient’s history, the appearance and unusually large size of the frontal lesion, it was unclear whether it was a demyelinating MS plaque, or an intra-axial tumour.
ISSN:0317-1671
2057-0155
DOI:10.1017/S031716710000425X