Annular elastolytic giant cell granuloma in an infant: Improvement after treatment with oral tranilast and topical pimecrolimus

Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous skin disease of unknown origin that is characterized clinically by annular patches with erythematous borders and hypopigmented centers and histologically by loss of elastic fibers and elastophagocytosis. We report a case of AEG...

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Bibliographic Details
Published in:Journal of the American Academy of Dermatology 2005-11, Vol.53 (5), p.S244-S246
Main Authors: Lee, Hae-Woong, Lee, Mi-Woo, Choi, Jee-Ho, Moon, Kee-Chan, Koh, Jai-Kyoung
Format: Article
Language:English
Subjects:
Administration, Oral
Administration, Topical
Anti-Allergic Agents - administration & dosage
Anti-Allergic Agents - therapeutic use
Biological and medical sciences
Dermatology
Elastic Tissue - pathology
Granuloma Annulare - drug therapy
Granuloma Annulare - pathology
Humans
Immunosuppressive Agents - administration & dosage
Immunosuppressive Agents - therapeutic use
Infant
Male
Medical sciences
ortho-Aminobenzoates - administration & dosage
ortho-Aminobenzoates - therapeutic use
Skin involvement in other diseases. Miscellaneous. General aspects
Tacrolimus - administration & dosage
Tacrolimus - analogs & derivatives
Tacrolimus - therapeutic use
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Summary:Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous skin disease of unknown origin that is characterized clinically by annular patches with erythematous borders and hypopigmented centers and histologically by loss of elastic fibers and elastophagocytosis. We report a case of AEGCG in an 8-month-old boy that was successfully treated with oral tranilast and topical pimecrolimus (Elidel 1.0% cream).
ISSN:0190-9622
1097-6787
DOI:10.1016/j.jaad.2005.02.013