Carbon Nanofiber-Based Glucose Biosensor

The use of highly activated carbon nanofibers for the design of catalytic electrochemical biosensors is demonstrated. The direct immobilization of enzymes onto the surface of carbon nanofibers is shown to be a highly efficient method for the development of a new class of very sensitive, stable, and...

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Bibliographic Details
Published in:Analytical chemistry (Washington) 2006-08, Vol.78 (15), p.5538-5542
Main Authors: Vamvakaki, Vicky, Tsagaraki, Katerina, Chaniotakis, Nikos
Format: Article
Language:English
Subjects:
Analytical chemistry
Biochemistry
Biological and medical sciences
Biosensing Techniques - methods
Biosensors
Biotechnology
Carbon
Chemistry
Electrochemical methods
Electrochemistry
Enzymes
Enzymes, Immobilized - chemistry
Exact sciences and technology
Fundamental and applied biological sciences. Psychology
Glucose
Glucose - analysis
Glucose Oxidase - chemistry
Graphite - chemistry
Hydrogen-Ion Concentration
Matrix
Methods. Procedures. Technologies
Nanotechnology
Nanotubes, Carbon - chemistry
Particle Size
Reproducibility of Results
Sensitivity and Specificity
Surface Properties
Various methods and equipments
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Summary:The use of highly activated carbon nanofibers for the design of catalytic electrochemical biosensors is demonstrated. The direct immobilization of enzymes onto the surface of carbon nanofibers is shown to be a highly efficient method for the development of a new class of very sensitive, stable, and reproducible electrochemical biosensors. These results establish the fact that the carbon nanofiber is the best matrix so far described for the development of biosensors, far superior to carbon nanotubes or graphite powder.
ISSN:0003-2700
1520-6882
DOI:10.1021/ac060551t