Disseminated Sporothix schenckii in a patient with AIDS

Sporothrix schenckii is a widespread dimorphic fungus which can cause cutaneous infection following local implantation. Disseminated sporotrichosis may occur in immunodeficient individuals but meningitis remains a rare complication. Diagnosis is usually difficult, requiring isolation of the organism...

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Bibliographic Details
Published in:The Journal of infection 2005-10, Vol.51 (3), p.e73-e77
Main Authors: Hardman, S., Stephenson, I., Jenkins, D.R., Wiselka, M.J., Johnson, E.M.
Format: Article
Language:English
Subjects:
Adult
AIDS-Related Opportunistic Infections - microbiology
Dermatomycoses - microbiology
Fatal Outcome
HIV
HIV Infections - complications
HIV-1
Humans
Male
Meningitis
Meningitis, Fungal - microbiology
Sporothrix - isolation & purification
Sporothrix schenckii
Sporotrichosis - microbiology
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Summary:Sporothrix schenckii is a widespread dimorphic fungus which can cause cutaneous infection following local implantation. Disseminated sporotrichosis may occur in immunodeficient individuals but meningitis remains a rare complication. Diagnosis is usually difficult, requiring isolation of the organism from the CSF or skin so appropriate treatment can be promptly initiated. We present the first case of S. schenckii meningitis reported in the UK in a patient with AIDS. He presented with insidious features of meningoencephalitis, hydrocephalus and multiple cutaneous lesions and failed to respond to therapy.
ISSN:0163-4453
1532-2742
DOI:10.1016/j.jinf.2004.07.001