Dementia associated with epilepsy

In this review, we explore the relationship between epilepsy and cognition and between epilepsy and dementia. Chronic epilepsy, particularly mesial temporal lobe epilepsy (MTLE) with hippocampal sclerosis, may be associated with impaired cognition, which can be secondary to uncontrolled seizures, to...

Full description

Saved in:
Bibliographic Details
Published in:International psychogeriatrics 2005-09, Vol.17 (s1), p.S195-S206
Main Authors: Caramelli, Paulo, Castro, Luiz Henrique Martins
Format: Article
Language:English
Subjects:
Aging - physiology
Cognition Disorders - etiology
Convulsions & seizures
Dementia
Dementia - etiology
Dementia - physiopathology
Epilepsy
Epilepsy, Temporal Lobe - complications
Hippocampus - pathology
Humans
Sclerosis - complications
Sclerosis - pathology
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In this review, we explore the relationship between epilepsy and cognition and between epilepsy and dementia. Chronic epilepsy, particularly mesial temporal lobe epilepsy (MTLE) with hippocampal sclerosis, may be associated with impaired cognition, which can be secondary to uncontrolled seizures, to adverse effects of antiepileptic drugs (AEDs) or to the underlying biological abnormality. The choice of an adequate AED with an appropriate dose regimen may lead to a favorable outcome. This feature is especially relevant in elderly patients with dementia and associated epilepsy, a vulnerable population in which the diagnosis of seizures can be difficult and for whom treatment guidelines are not yet available. Based on available information and on data derived from studies with other populations, recommendations for the management of these patients are presented.
ISSN:1041-6102
1741-203X
DOI:10.1017/S1041610205002024