Plasma homocysteine and microvascular and macrovascular complications in type 1 diabetes: a cross‐sectional nested case–control study

. Objectives.  To examine the independent relationship between plasma total homocysteine (tHcy) and microvascular and macrovascular complications. Design.  We performed a cross‐sectional nested case–control study from the EURODIAB Prospective Complications Study. Setting.  A hospital‐based multicent...

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Bibliographic Details
Published in:Journal of internal medicine 2005-11, Vol.258 (5), p.450-459
Main Authors: SOEDAMAH‐MUTHU, S. S., CHATURVEDI, N., TEERLINK, T., IDZIOR‐WALUS, B., FULLER, J. H., STEHOUWER, C. D. A.
Format: Article
Language:English
Subjects:
Adult
albuminuria
Albuminuria - blood
Albuminuria - complications
Biological and medical sciences
cardiovascular disease
Cardiovascular Diseases - blood
Cardiovascular Diseases - complications
Case-Control Studies
Cross-Sectional Studies
Diabetes Mellitus, Type 1 - blood
Diabetes Mellitus, Type 1 - complications
Diabetes. Impaired glucose tolerance
Diabetic Angiopathies - blood
Diabetic Retinopathy - blood
Diabetic Retinopathy - complications
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
Etiopathogenesis. Screening. Investigations. Target tissue resistance
Female
General aspects
Glomerular Filtration Rate - physiology
homocysteine
Homocysteine - blood
Humans
hypertension
Hypertension - blood
Hypertension - complications
Male
Medical sciences
Microcirculation
Prospective Studies
retinopathy
Risk Factors
type 1 diabetes
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Summary:. Objectives.  To examine the independent relationship between plasma total homocysteine (tHcy) and microvascular and macrovascular complications. Design.  We performed a cross‐sectional nested case–control study from the EURODIAB Prospective Complications Study. Setting.  A hospital‐based multicentre study at 24 centres in 13 European countries. Subjects.  A total of 533 type 1 diabetic patients, diagnosed at
ISSN:0954-6820
1365-2796
DOI:10.1111/j.1365-2796.2005.01560.x