PDQ Wizard: automated prioritization and characterization of gene and protein lists using biomedical literature

• Published in: Bioinformatics 2006-08, Vol.22 (16), p.2055-2057
• Main Authors: Grimes, G. R., Wen, T. Q., Mewissen, M., Baxter, R. M., Moodie, S., Beattie, J. S., Ghazal, P.
• Format: Article
• Language: English
• Subjects: Abstracting and Indexing as Topic; Animals; Biological and medical sciences; Computational Biology - methods; Databases, Bibliographic; Databases, Genetic; Databases, Protein; Fundamental and applied biological sciences. Psychology; General aspects; Humans; Information Storage and Retrieval; Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects); Natural Language Processing; Pattern Recognition, Automated; Programming Languages; PubMed; Software; User-Computer Interface
• ISSN: 1367-4803; 1460-2059; 1367-4811
• DOI: 10.1093/bioinformatics/btl342

PDQ Wizard automates the process of interrogating biomedical references using large lists of genes, proteins or free text. Using the principle of linkage through co-citation biologists can mine PubMed with these proteins or genes to identify relationships within a biological field of interest. In addition, PDQ Wizard provides novel features to define more specific relationships, highlight key publications describing those activities and relationships, and enhance protein queries. PDQ Wizard also outputs a metric that can be used for prioritization of genes and proteins for further research. Availability: PDQ Wizard is freely available from Contact:[e-mail] Supplementary Information: Supplementary Data are available