Regression rate of clinical HPV infection of the lower genital tract during pregnancy after laser CO2 surgery

The objective of the study was to evaluate the effects of laser CO2 surgery during pregnancy to prevent clinical HPV infection recurrence after delivery and vertical infection. A case-control study was performed on 280 pregnant women affected by clinical HPV infection treated during pregnancy with 2...

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Bibliographic Details
Published in:Clinical and experimental obstetrics & gynecology 2006, Vol.33 (2), p.93-95
Main Authors: Frega, A, Baiocco, E, Pace, S, Palazzo, A, Iacovelli, R, Biamontil, A, Moscarini, M, Stentella, P
Format: Article
Language:English
Subjects:
Carbon Dioxide
Condylomata Acuminata - surgery
Condylomata Acuminata - virology
Female
Follow-Up Studies
Genital Diseases, Female - surgery
Genital Diseases, Female - virology
Humans
Laser Therapy
Postpartum Period
Pregnancy
Pregnancy Complications, Infectious - surgery
Pregnancy Outcome
Pregnancy Trimester, Second
Recurrence
Retreatment - statistics & numerical data
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Summary:The objective of the study was to evaluate the effects of laser CO2 surgery during pregnancy to prevent clinical HPV infection recurrence after delivery and vertical infection. A case-control study was performed on 280 pregnant women affected by clinical HPV infection treated during pregnancy with 256 women treated three months after delivery. Follow-up was performed for a minimum of three colposcopic examinations for two years. Recurrence rates were calculated considering the number of positive findings for at least one colposcopic examination confirmed by biopsy after a negative control in a year. Statistical comparison of rates was performed by chi-squared and Fisher's exact test. Recurrence rates were higher in the women treated in postpartum (p < .01) than in the group treated during gestation (p < .005). Clinical HPV infections treated during the second trimester of pregnancy showed a sensitive decrease in recurrence-rate of infection. Rarity of respiratory papillomatosis makes conclusions inconsistent for the prevention of vertical infection.
ISSN:0390-6663