Malignant nonfunctioning islet cell tumor of the pancreas with intrasplenic growth: a case report

<正>BACKGROUND: We reported a case of malignant nonfunction islet cell tumor (10.0 cm in diameter) of the pancreas, with malignant histological features and splenic infiltration. The case is rare, and few reports have been published. METHODS: A 46-year-old woman with a vague pain in the...

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Bibliographic Details
Published in:Hepatobiliary & pancreatic diseases international 2006-08, Vol.5 (3), p.471-473
Main Authors: Wang, Hong-Jiang, Zhao, Zuo-Wei, Luo, Hai-Feng, Wang, Zhong-Yu
Format: Article
Language:English
Subjects:
Carcinoma, Islet Cell - diagnosis
Carcinoma, Islet Cell - pathology
cell
growth
Humans
intrasplenic
islet
Middle Aged
nonfunctioning
Pancreatic Neoplasms - diagnosis
Pancreatic Neoplasms - pathology
Splenic Neoplasms - diagnosis
Splenic Neoplasms - pathology
Splenic Neoplasms - secondary
tumor
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Summary:<正>BACKGROUND: We reported a case of malignant nonfunction islet cell tumor (10.0 cm in diameter) of the pancreas, with malignant histological features and splenic infiltration. The case is rare, and few reports have been published. METHODS: A 46-year-old woman with a vague pain in the left upper quadrant for 3 months was found to have a tumor in the spleen. Ultrasonography and computed tomography demonstrated a well-defined pancreatic tumor of 8.2×10.0 cm in size, her serum levels of pancreatic hormones were within normal limits. RESULTS: Splenectomy combined with pancreatectomy was performed for the tail of the pancreas. Resected specimens showed a malignant nonfunctioning islet cell tumor invading the spleen. CONCLUSIONS: The growth pattern of the tumor causes malignant features. Resection of the tumor should be performed by enucleation, pancreaticoduodenectomy or distal pancreatectomy.
ISSN:1499-3872