Composition, Enantiomeric Distribution, and Antibacterial Activity of the Essential Oil of Achillea ligustica All. from Corsica

The essential oil of Achillea ligustica from Corsica was investigated by gas chromatography (GC) and gas chromatography−mass spectrometry (GC-MS). A total of 82 compounds representing 94.0% of the oil were tentatively identified. The main constituents were the camphane derivatives, representing >...

Full description

Saved in:
Bibliographic Details
Published in:Journal of agricultural and food chemistry 2006-08, Vol.54 (17), p.6308-6313
Main Authors: Filippi, Jean-Jacques, Lanfranchi, Don-Antoine, Prado, Soizic, Baldovini, Nicolas, Meierhenrich, Uwe J
Format: Article
Language:English
Subjects:
Achillea
Achillea - chemistry
Achillea ligustica
alcohols
animal pathogenic bacteria
Anti-Bacterial Agents - pharmacology
antibacterial properties
Aroma and flavouring agent industries
bacteria
Biological and medical sciences
chemical composition
Chromatography, Gas
enantiomers
essential oils
Food industries
Food microbiology
France
Fundamental and applied biological sciences. Psychology
gas chromatography
Gas Chromatography-Mass Spectrometry
Gram-Negative Bacteria - drug effects
Gram-Positive Bacteria - drug effects
Magnetic Resonance Spectroscopy
mass spectrometry
Oils, Volatile - chemistry
Oils, Volatile - pharmacology
Santolina
santolina alcohol
Stereoisomerism
Streptomyces
Streptomyces - drug effects
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The essential oil of Achillea ligustica from Corsica was investigated by gas chromatography (GC) and gas chromatography−mass spectrometry (GC-MS). A total of 82 compounds representing 94.0% of the oil were tentatively identified. The main constituents were the camphane derivatives, representing >30% (camphor, 21.3%; borneol, 6.2%; bornyl acetate, 3.5%) of the whole oil, and santolina alcohol (19.3%). The enantiomeric distribution of 8 chiral constituents was determined by GC-MS using two enantioselective stationary phases (DIME-β-CD and Lipodex-E). Racemic santolina alcohol, required for optimization of the enantioselective GC conditions, was prepared by an original two-step synthesis from 2,5-dimethylhexa-2,4-diene. The whole essential oil was tested for its antibacterial activity against a wide range of bacteria using a paper disk method. The results show a promising activity against Streptomyces species. Keywords: Achillea ligustica; essential oil composition; enantioselective analysis; antibacterial properties; santolina alcohol
ISSN:0021-8561
1520-5118
DOI:10.1021/jf060752y