Rosetoid schwannoma (neuroblastoma‐like) in association with an anetoderma

Background:  We report an additional case of an extremely uncommon but distinctive histological variant of benign schwannoma, which was previously designated as neuroblastoma‐like schwannoma by Goldblum et al. Methods:  A 29‐year‐old woman referred to a 6‐year‐history of an atrofic macule. Its clini...

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Bibliographic Details
Published in:Journal of cutaneous pathology 2006-08, Vol.33 (8), p.573-576
Main Authors: Vélez, Dolores, Reina Duran, Teresa, Pérez‐Gala, Silvia, Fernández, Javier Fraga
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Dermatology
Elastic Tissue - pathology
Female
Humans
Medical sciences
Neurilemmoma - chemistry
Neurilemmoma - complications
Neurilemmoma - pathology
Neurology
S100 Proteins - analysis
Skin Diseases - complications
Skin Diseases - pathology
Tumors of the nervous system. Phacomatoses
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Summary:Background:  We report an additional case of an extremely uncommon but distinctive histological variant of benign schwannoma, which was previously designated as neuroblastoma‐like schwannoma by Goldblum et al. Methods:  A 29‐year‐old woman referred to a 6‐year‐history of an atrofic macule. Its clinical appearance was similar to that of an anetoderma. Results:  A cutaneous biopsy showed findings consistent with a neuroblastoma‐like schwannoma with the following peculiar features: (i) Being fully composed of rosette‐like structures. (ii) Association to an anetoderma. Conclusions:  Because neither the histological pattern nor the type of tumor allows a differential diagnosis with neuroblastoma, we propose the descriptive term of rosetoid schwannoma. And to our knowledge, this will be the first case reported of rosetoid schwannoma associated to anetoderma.
ISSN:0303-6987
1600-0560
DOI:10.1111/j.1600-0560.2006.00480.x