The relationship of the round window membrane to the cochlear aqueduct shown in three-dimensional imaging

The round window membrane and cochlear aqueduct complex in the guinea pig are reconstructed with 3D-imaging, using orthogonal plane fluorescence optical sectioning (OPFOS). The 3D-images show that the periotic duct and the aqueduct are connected to a pouch-like extension of the round window. The fun...

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Bibliographic Details
Published in:Hearing research 2005-11, Vol.209 (1), p.19-23
Main Authors: Hofman, R., Segenhout, J.M., Albers, F.W.J., Wit, H.P.
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Cochlear aqueduct
Cochlear Aqueduct - anatomy & histology
Drug toxicity and drugs side effects treatment
Ear and associated structures. Auditory pathways and centers. Hearing. Vocal organ. Phonation. Sound production. Echolocation
Female
Flow resistance
Fundamental and applied biological sciences. Psychology
Guinea Pigs - anatomy & histology
Imaging, Three-Dimensional - instrumentation
Imaging, Three-Dimensional - methods
Medical sciences
OPFOS
Perilymph
Pharmacology. Drug treatments
Round window membrane
Round Window, Ear - anatomy & histology
Toxicity: respiratory system, ent, stomatology
Vertebrates: nervous system and sense organs
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Summary:The round window membrane and cochlear aqueduct complex in the guinea pig are reconstructed with 3D-imaging, using orthogonal plane fluorescence optical sectioning (OPFOS). The 3D-images show that the periotic duct and the aqueduct are connected to a pouch-like extension of the round window. The function of this may be regulation of aqueduct flow resistance under the influence of a pressure difference between inner ear fluid and middle ear.
ISSN:0378-5955
1878-5891
DOI:10.1016/j.heares.2005.06.004