Computed Tomography in the Evaluation of Cystic Fibrosis Lung Disease

The first report of computed tomography (CT) scanning to monitor cystic fibrosis (CF)-related lung disease was published in 1986. Further publications followed, but in general there was little interest in this technique until recently. Two factors in particular have led to this increased interest. F...

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Bibliographic Details
Published in:American journal of respiratory and critical care medicine 2005-11, Vol.172 (10), p.1246-1252
Main Authors: Brody, Alan S, Tiddens, Harm A. W. M, Castile, Robert G, Coxson, Harvey O, de Jong, Pim A, Goldin, Jonathan, Huda, Walter, Long, Frederick R, McNitt-Gray, Michael, Rock, Michael, Robinson, Terry E, Sagel, Scott D, CT Scanning in Cystic Fibrosis Special Interest Group
Format: Article
Language:English
Subjects:
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Chronic obstructive pulmonary disease, asthma
Cohort analysis
Cystic fibrosis
Cystic Fibrosis - diagnostic imaging
Drug dosages
Humans
Intensive care medicine
Investigative techniques, diagnostic techniques (general aspects)
Lung - diagnostic imaging
Lung diseases
Lungs
Medical imaging
Medical sciences
Patients
Pneumology
Quantitative analysis
Radiation
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Respiratory Function Tests
Respiratory system
Sensitivity and Specificity
Tomography
Tomography, X-Ray Computed - methods
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Summary:The first report of computed tomography (CT) scanning to monitor cystic fibrosis (CF)-related lung disease was published in 1986. Further publications followed, but in general there was little interest in this technique until recently. Two factors in particular have led to this increased interest. First is an increasing realization that pulmonary function tests, long the mainstay of CF evaluation, often underestimate the presence and severity of mild and moderate lung disease. Second is the need for more sensitive outcome measures to assess new therapies. This had led to new interest and a series of important publications. The goal of this article is to present the current status of CT scanning in CF.
ISSN:1073-449X
1535-4970
DOI:10.1164/rccm.200503-401PP