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Transcranial Doppler Monitoring during Stenting of the Carotid Bifurcation: Evaluation of Two Different Distal Protection Devices in Preventing Embolization

Purpose: To compare the efficacy of 2 emboli protection devices in preventing embolization during carotid artery stenting (CAS). Methods: The GuardWire distal occlusion system (n=19) and the distal FilterWire EX (n=12) were compared in 31 consecutive patients (24 men; mean age 71±10 years) monitored...

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Published in:Journal of endovascular therapy 2006-08, Vol.13 (4), p.436-442
Main Authors: Rubartelli, Paolo, Brusa, Giulia, Arrigo, Alessandro, Abbadessa, Francesco, Giachero, Corinna, Vischi, Massimo, Ricca, Maria Maddalena, Ottonello, Gian Andrea
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cited_by cdi_FETCH-LOGICAL-c328t-bb1122ff197f8cfa61084980945944e42b0afec5f5738c101e097fbd7a25281f3
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container_issue 4
container_start_page 436
container_title Journal of endovascular therapy
container_volume 13
creator Rubartelli, Paolo
Brusa, Giulia
Arrigo, Alessandro
Abbadessa, Francesco
Giachero, Corinna
Vischi, Massimo
Ricca, Maria Maddalena
Ottonello, Gian Andrea
description Purpose: To compare the efficacy of 2 emboli protection devices in preventing embolization during carotid artery stenting (CAS). Methods: The GuardWire distal occlusion system (n=19) and the distal FilterWire EX (n=12) were compared in 31 consecutive patients (24 men; mean age 71±10 years) monitored with transcranial Doppler for microembolic signals before, during, and after CAS. The choice of the protection device was based on availability and on the patency of the contralateral carotid artery. Results: The baseline characteristics were similar in the patients treated under protection from either device. Placement and retrieval of the protection device, stenting, and postdilation were technically successful in all patients. Two patients suffered a transient ischemic attack shortly after the procedure; no other adverse cardiovascular events occurred at 30 days. Compared to the GuardWire, the use of the FilterWire was associated with more microembolic signals during stent deployment (77.4±33.5 versus 1.07±1.94, p
doi_str_mv 10.1583/05-1804MR.1
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Methods: The GuardWire distal occlusion system (n=19) and the distal FilterWire EX (n=12) were compared in 31 consecutive patients (24 men; mean age 71±10 years) monitored with transcranial Doppler for microembolic signals before, during, and after CAS. The choice of the protection device was based on availability and on the patency of the contralateral carotid artery. Results: The baseline characteristics were similar in the patients treated under protection from either device. Placement and retrieval of the protection device, stenting, and postdilation were technically successful in all patients. Two patients suffered a transient ischemic attack shortly after the procedure; no other adverse cardiovascular events occurred at 30 days. Compared to the GuardWire, the use of the FilterWire was associated with more microembolic signals during stent deployment (77.4±33.5 versus 1.07±1.94, p&lt;0.0001), postdilation (63.9±21.0 versus 2.06±2.58, p&lt;0.0001), and retrieval of the protection device (21.4±15.4 versus 10.9±8.3, p=0.051). Consequently, the total amount of microembolic signals during the procedure was higher when the filter device was employed (183.0±42.1 versus 31.7±12.0, p&lt;0.0001). Conclusion: The distal occlusion device appears to be more effective than the filter in reducing distal embolization detected by transcranial Doppler monitoring.</description><identifier>ISSN: 1526-6028</identifier><identifier>EISSN: 1545-1550</identifier><identifier>DOI: 10.1583/05-1804MR.1</identifier><identifier>PMID: 16928156</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Aged ; Aged, 80 and over ; Angioplasty, Balloon ; Carotid Stenosis - diagnostic imaging ; Carotid Stenosis - therapy ; Cerebrovascular Circulation ; Comparative studies ; Female ; Heart surgery ; Humans ; Intracranial Embolism - prevention &amp; control ; Ischemic Attack, Transient - prevention &amp; control ; Male ; Middle Aged ; Monitoring, Physiologic - methods ; Patients ; Stents ; Treatment Outcome ; Ultrasonography, Doppler, Transcranial ; Veins &amp; arteries</subject><ispartof>Journal of endovascular therapy, 2006-08, Vol.13 (4), p.436-442</ispartof><rights>2006 SAGE Publications</rights><rights>Copyright Alliance Communications Group, A Division of Allen Press, Inc. Aug 2006</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c328t-bb1122ff197f8cfa61084980945944e42b0afec5f5738c101e097fbd7a25281f3</citedby><cites>FETCH-LOGICAL-c328t-bb1122ff197f8cfa61084980945944e42b0afec5f5738c101e097fbd7a25281f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904,79110</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16928156$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rubartelli, Paolo</creatorcontrib><creatorcontrib>Brusa, Giulia</creatorcontrib><creatorcontrib>Arrigo, Alessandro</creatorcontrib><creatorcontrib>Abbadessa, Francesco</creatorcontrib><creatorcontrib>Giachero, Corinna</creatorcontrib><creatorcontrib>Vischi, Massimo</creatorcontrib><creatorcontrib>Ricca, Maria Maddalena</creatorcontrib><creatorcontrib>Ottonello, Gian Andrea</creatorcontrib><title>Transcranial Doppler Monitoring during Stenting of the Carotid Bifurcation: Evaluation of Two Different Distal Protection Devices in Preventing Embolization</title><title>Journal of endovascular therapy</title><addtitle>J Endovasc Ther</addtitle><description>Purpose: To compare the efficacy of 2 emboli protection devices in preventing embolization during carotid artery stenting (CAS). Methods: The GuardWire distal occlusion system (n=19) and the distal FilterWire EX (n=12) were compared in 31 consecutive patients (24 men; mean age 71±10 years) monitored with transcranial Doppler for microembolic signals before, during, and after CAS. The choice of the protection device was based on availability and on the patency of the contralateral carotid artery. Results: The baseline characteristics were similar in the patients treated under protection from either device. Placement and retrieval of the protection device, stenting, and postdilation were technically successful in all patients. Two patients suffered a transient ischemic attack shortly after the procedure; no other adverse cardiovascular events occurred at 30 days. Compared to the GuardWire, the use of the FilterWire was associated with more microembolic signals during stent deployment (77.4±33.5 versus 1.07±1.94, p&lt;0.0001), postdilation (63.9±21.0 versus 2.06±2.58, p&lt;0.0001), and retrieval of the protection device (21.4±15.4 versus 10.9±8.3, p=0.051). Consequently, the total amount of microembolic signals during the procedure was higher when the filter device was employed (183.0±42.1 versus 31.7±12.0, p&lt;0.0001). 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Methods: The GuardWire distal occlusion system (n=19) and the distal FilterWire EX (n=12) were compared in 31 consecutive patients (24 men; mean age 71±10 years) monitored with transcranial Doppler for microembolic signals before, during, and after CAS. The choice of the protection device was based on availability and on the patency of the contralateral carotid artery. Results: The baseline characteristics were similar in the patients treated under protection from either device. Placement and retrieval of the protection device, stenting, and postdilation were technically successful in all patients. Two patients suffered a transient ischemic attack shortly after the procedure; no other adverse cardiovascular events occurred at 30 days. Compared to the GuardWire, the use of the FilterWire was associated with more microembolic signals during stent deployment (77.4±33.5 versus 1.07±1.94, p&lt;0.0001), postdilation (63.9±21.0 versus 2.06±2.58, p&lt;0.0001), and retrieval of the protection device (21.4±15.4 versus 10.9±8.3, p=0.051). Consequently, the total amount of microembolic signals during the procedure was higher when the filter device was employed (183.0±42.1 versus 31.7±12.0, p&lt;0.0001). Conclusion: The distal occlusion device appears to be more effective than the filter in reducing distal embolization detected by transcranial Doppler monitoring.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>16928156</pmid><doi>10.1583/05-1804MR.1</doi><tpages>7</tpages></addata></record>
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ispartof Journal of endovascular therapy, 2006-08, Vol.13 (4), p.436-442
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1545-1550
language eng
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source SAGE
subjects Aged
Aged, 80 and over
Angioplasty, Balloon
Carotid Stenosis - diagnostic imaging
Carotid Stenosis - therapy
Cerebrovascular Circulation
Comparative studies
Female
Heart surgery
Humans
Intracranial Embolism - prevention & control
Ischemic Attack, Transient - prevention & control
Male
Middle Aged
Monitoring, Physiologic - methods
Patients
Stents
Treatment Outcome
Ultrasonography, Doppler, Transcranial
Veins & arteries
title Transcranial Doppler Monitoring during Stenting of the Carotid Bifurcation: Evaluation of Two Different Distal Protection Devices in Preventing Embolization
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