Adenoendocrine cell carcinoma of the gallbladder: report of a case

Adenoendocrine cell carcinoma of the gallbladder is an uncommon form of cancer. We treated a 36-year-old woman who came to us with a chief complaint of abdominal pain. The abnormality was diagnosed to be a tumor-like mass in the gallbladder, and adenomyomatosis of the gallbladder was strongly suspec...

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Bibliographic Details
Published in:Surgery today (Tokyo, Japan) Japan), 2006, Vol.36 (9), p.849-852
Main Authors: Tsuchiya, Atsuo, Endo, Yoshiyuki, Yazawa, Takashi, Saito, Atsuko, Inoue, Norio
Format: Article
Language:English
Subjects:
Adenocarcinoma - pathology
Adenocarcinoma - surgery
Adult
Carcinoma, Neuroendocrine - pathology
Carcinoma, Neuroendocrine - surgery
Cholecystectomy, Laparoscopic
Female
Gallbladder Neoplasms - pathology
Gallbladder Neoplasms - surgery
Humans
Immunohistochemistry
Treatment Outcome
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Summary:Adenoendocrine cell carcinoma of the gallbladder is an uncommon form of cancer. We treated a 36-year-old woman who came to us with a chief complaint of abdominal pain. The abnormality was diagnosed to be a tumor-like mass in the gallbladder, and adenomyomatosis of the gallbladder was strongly suspected. A laparoscopic cholecystectomy was successfully performed, and the histopathological finding was adenoendocrine cell carcinoma of the gallbladder. The tumor cells of the small round cell carcinoma partly stained positively for synaptophysin, neuron-specific enolase, and CD 56, while adenocarcinoma cells showed positive reactions to keratin, which was thus suggestive of adenoendocrine cell carcinoma. The patient is alive and doing well at 12 months after the treatment.
ISSN:0941-1291
DOI:10.1007/s00595-006-3249-y