Phenotype of peripheral blood lymphocytes and serum immunoglobulin concentration in patients with early rheumatoid arthritis

We studied the phenotype of peripheral blood lymphocytes and serum immunoglobulin concentration in patients with early rheumatoid arthritis and rheumatoid arthritis of more than 12 months duration. Subpopulations of CDIgM+, CD25+, and HLA-DR+ lymphocytes and IgA concentration differed in these group...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2006-01, Vol.141 (1), p.84-86
Main Authors: Timofeev, V T, Shostak, N A, Anichkov, D A, Potanin, A Yu
Format: Article
Language:English
Subjects:
Aged
Arthritis, Rheumatoid - diagnosis
Female
HLA-DR Antigens - analysis
Humans
Immunoglobulin A - blood
Immunoglobulin G - blood
Lymphocytes - immunology
Male
Middle Aged
Receptors, Fc - analysis
Receptors, Immunologic - analysis
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Summary:We studied the phenotype of peripheral blood lymphocytes and serum immunoglobulin concentration in patients with early rheumatoid arthritis and rheumatoid arthritis of more than 12 months duration. Subpopulations of CDIgM+, CD25+, and HLA-DR+ lymphocytes and IgA concentration differed in these groups of patients with rheumatoid arthritis. The count of lymphocytes carrying CDIgM+ and HLA-DR+ receptors correlated with activity of rheumatoid arthritis.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-006-0100-9