Pancreatic primary lymphoma: a case report and review of the literature

<正>BACKGROUND: Primary pancreatic lymphoma is a rare but treatable malignancy ( less than 1% of pancreatic tumors) that may be clinically confused with pancreatic adenocarcinoma. METHODS: In a patient with upper abdominal pain, ultra-sonography and CT detected a mass in pancreatic head...

Full description

Saved in:
Bibliographic Details
Published in:Hepatobiliary & pancreatic diseases international 2005-11, Vol.4 (4), p.622-626
Main Authors: Ji, Yuan, Kuang, Tian-Tao, Tan, Yun-Shan, Chen, Ying, Zeng, Hai-Ying, Jin, Da-Yong
Format: Article
Language:English
Subjects:
Bcl-6
CD20
Diagnosis, Differential
Humans
lymphoma
Lymphoma - diagnostic imaging
Lymphoma - pathology
Lymphoma - surgery
Male
Middle Aged
pancreas
Pancreatic Neoplasms - diagnostic imaging
Pancreatic Neoplasms - pathology
Pancreatic Neoplasms - surgery
Radiography
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:<正>BACKGROUND: Primary pancreatic lymphoma is a rare but treatable malignancy ( less than 1% of pancreatic tumors) that may be clinically confused with pancreatic adenocarcinoma. METHODS: In a patient with upper abdominal pain, ultra-sonography and CT detected a mass in pancreatic head, which compressed the common bile duct. The patient received a Wliipple’s operation and intraoperative frozen sections of the mass showed an anaplastic carcinoma. Immu-nohistochemical staining was used to indicate the origin and prognosis of tumor. RESULTS: Grossly the tumor involved the pancreatic head, soft in consistence and invaded part of the gastric wall. His-tologically, the tumor was composed mainly of large and moderate neoplastic cells, which were diffusely positive for CD20 and Bcl-6 antigens, indicating the features of diffusely large B cell lymphoma. CONCLUSIONS : The proper diagnosis of the tumor should be made with CD20 and Bcl-6 immunohistochemical study. Radical surgery is indicated for resectable carcinoma but not for a chemosensitive lymphoma.
ISSN:1499-3872