Tendon allografts in the knee

[...]allografts have been used for primary ACL reconstruction [4], and also to reconstruct the posterior cruciate ligament [5], medial collateral ligament [6], lateral collateral ligament [7], and the extensor mechanism of the knee [8].2 Antigenicity and infection The majority of the antigeneic load...

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Bibliographic Details
Published in:The knee 2005-12, Vol.12 (6), p.401-404
Main Authors: McDermott, Ian, Thomas, N.P.
Format: Article
Language:English
Subjects:
Anterior Cruciate Ligament - surgery
Humans
Knee
Knee Joint - surgery
Ligaments
Reconstructive Surgical Procedures - methods
Skin & tissue grafts
Sports medicine
Tendons
Tendons - transplantation
Transplantation, Homologous
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Summary:[...]allografts have been used for primary ACL reconstruction [4], and also to reconstruct the posterior cruciate ligament [5], medial collateral ligament [6], lateral collateral ligament [7], and the extensor mechanism of the knee [8].2 Antigenicity and infection The majority of the antigeneic load of tendon allograft tissue is from the cellular component, and transplanted fresh tendon allografts can incite a marked inflammatory and rejection response [9]. The main concern in the primary ACL reconstruction, however, seems to be over the slower remodelling of allograft tissue, with the potential for subsequent stretching or rupture of the graft. [...]although their use can be recommended, caution with post-operative rehabilitation regimes and return to full sporting activities would seem wise.
ISSN:0968-0160
1873-5800
DOI:10.1016/j.knee.2005.08.005