Genetic diversity of BVDV: Consequences for classification and molecular epidemiology

Genetic typing of bovine viral diarrhoea virus (BVDV) is important for the precise classification of viruses as well as for the development of molecular epidemiology. BVDV isolates were usually typed based on comparison of genomic sequences from the 5′-untranslated region (5′-UTR), N pro and E2 regi...

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Bibliographic Details
Published in:Preventive veterinary medicine 2005-11, Vol.72 (1), p.31-35
Main Authors: Vilcek, S., Durkovic, B., Kolesarova, M., Paton, D.J.
Format: Article
Language:English
Subjects:
Animals
Bovine Virus Diarrhea-Mucosal Disease - epidemiology
Bovine Virus Diarrhea-Mucosal Disease - virology
BVDV
Cattle
Diarrhea Viruses, Bovine Viral - classification
Diarrhea Viruses, Bovine Viral - genetics
Genetic typing
Genetic Variation - genetics
Genotype
Molecular Epidemiology
Pestivirus
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Summary:Genetic typing of bovine viral diarrhoea virus (BVDV) is important for the precise classification of viruses as well as for the development of molecular epidemiology. BVDV isolates were usually typed based on comparison of genomic sequences from the 5′-untranslated region (5′-UTR), N pro and E2 region. Recently we have identified 11 genetic groups (subgenotypes) of BVDV-1. Our further experiments confirmed a new subgenotype, BVDV-1k, isolated from cattle in Switzerland. BVDV isolates from India were typed as BVDV-1b whereas BVDV-1c is a predominant subgenotype in Australia. The results of genetic typing of BVDV indicate that distribution of subgenotypes has no relationship to the geographic origin of viral isolates.
ISSN:0167-5877
1873-1716
DOI:10.1016/j.prevetmed.2005.08.004