Development of a computer-aided diagnosis system for a new modality of renal replacement therapy: an integrated approach combining both peritoneal dialysis and hemodialysis

The authors developed a computer-aided diagnosis system that includes a simple clinical test for the chronic renal disease patient who needs an integrated approach that combines both peritoneal dialysis and hemodialysis (PD–HD therapy). In this case study, the system simulated and estimated the dial...

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Bibliographic Details
Published in:Computers in biology and medicine 2005-12, Vol.35 (10), p.845-861
Main Authors: Hamada, Hiroyuki, Namoto, Shinji, Yamada, Ryo, Yamashita, Akihiro C., Ishizaki, Makoto, Okamoto, Masahiro
Format: Article
Language:English
Subjects:
Computer applications
Computer Simulation
Computer-aided diagnosis
Diagnosis
Dialysis Solutions - pharmacokinetics
Haemodialysis
Health care
Hemodialysis
Humans
Kidney Failure, Chronic - therapy
Medicine
Models, Biological
Optimal treatment
Peritoneal dialysis
Peritoneal Dialysis - methods
Pharmacokinetics
Renal Dialysis - methods
Software
Therapeutic monitoring
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Summary:The authors developed a computer-aided diagnosis system that includes a simple clinical test for the chronic renal disease patient who needs an integrated approach that combines both peritoneal dialysis and hemodialysis (PD–HD therapy). In this case study, the system simulated and estimated the dialysis outcome, the ultrafiltration volume and nutritional analysis by employing a pharmacokinetic model, and assessed the peritoneal permeable enhancement that can be a grave complication with peritoneal dialysis. This system requires only a minimum amount of nursing time and may be able to predict the optimal treatment schedule for PD–HD therapy and provide therapeutic monitoring in long-term peritoneal dialysis.
ISSN:0010-4825
1879-0534
DOI:10.1016/j.compbiomed.2004.09.002