ACE genotype may have an effect on single versus multiple set preferences in strength training

A polymorphic variant of the human angiotensin converting enzyme (ACE) gene was identified. The 'D' (rather than 'I') variant was associated with improvements in strength related to physical training. We set out to determine whether the response to different patterns of strength...

Full description

Saved in:
Bibliographic Details
Published in:European journal of applied physiology 2005-09, Vol.95 (1), p.20-26
Main Authors: Colakoglu, Muzaffer, Cam, F Sirri, Kayitken, Bulent, Cetinoz, Firat, Colakoglu, Sule, Turkmen, Mustafa, Sayin, Metin
Format: Article
Language:English
Subjects:
Adult
Exercise - physiology
Genotype
Genotype & phenotype
Humans
Male
Peptidyl-Dipeptidase A - genetics
Physical Education and Training - methods
Physical Exertion - physiology
Physical Fitness - physiology
Sports training
Weight Lifting - physiology
Weightlifting
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A polymorphic variant of the human angiotensin converting enzyme (ACE) gene was identified. The 'D' (rather than 'I') variant was associated with improvements in strength related to physical training. We set out to determine whether the response to different patterns of strength training might also differ. Ninty-nine Caucasian male non-elite athletes were randomly allocated into one of three groups: 31 non-training/control (CG: 31), single-set (SSG: 35) and multiple-set (MSG: 33). SSG and MSG trained three times a week for 6 weeks. Both training groups were underwent a strength-training program with two mesocycles (12-15 repetition maximum (RM) and 8-12 RM mesocycles). One RM loads in half squat and bench press were assessed before training and after the first and second mesocycles. ACE polymorphisms analysed by polymerase chain reaction (PCR) methods. Subjects with ACE II genotype in the MST group had improved strength development in 12-15 RM, while SST and MST groups had similar gains in 8-12 RM. Subjects with ACE DD genotype in both the SSG and the MSG had similar benefits from both 12-15 RM and 8-12 RM. Strength gains for subjects with ACE ID genotype in the SSG were similar to MSG gains in response to 8-12 RM loads but not with 12-15 RM loads. Additionally, subjects with DD genotype had superior strength gains in both strength training groups. Tailoring strength training programmes (single-set vs. multiple set) according to the athlete's ACE genotype may be advantageous.
ISSN:1439-6319
1439-6327
DOI:10.1007/s00421-005-1335-2