Effects of baseline serum levels of Se on markers of eccentric exercise-induced muscle injury

Inflammation and oxidative stress have been implicated in the mechanism of eccentric exercise‐induced muscle injury. This study examined whether baseline serum levels of selenium (Se), a trace element that participates in both antioxidant and anti‐inflammatory systems, affects the overall response t...

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Bibliographic Details
Published in:BioFactors (Oxford) 2006, Vol.26 (3), p.161-170
Main Authors: Milias, G.A., Nomikos, T., Fragopoulou, E., Athanasopoulos, S., Antonopoulou, S.
Format: Article
Language:English
Subjects:
Adult
Analysis of Variance
Antioxidants - administration & dosage
Antioxidants - metabolism
Arm
Biomarkers - blood
creatine kinase
Creatine Kinase - blood
Diet Records
eccentric exercise-induced muscle injury
Exercise - physiology
Exercise Test - methods
Humans
inflammation
L-Lactate Dehydrogenase - blood
Male
Muscle Strength Dynamometer
Muscle, Skeletal - injuries
Nutritional Status
oxidative stress
Oxidative Stress - physiology
Range of Motion, Articular - physiology
Reference Values
Selenium
Selenium - administration & dosage
Selenium - blood
Time Factors
Torque
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Summary:Inflammation and oxidative stress have been implicated in the mechanism of eccentric exercise‐induced muscle injury. This study examined whether baseline serum levels of selenium (Se), a trace element that participates in both antioxidant and anti‐inflammatory systems, affects the overall response to injury. Thirteen males performed 36 maximal eccentric actions with the elbow flexors of the non‐dominant arm on a motorized dynamometer. Venous blood samples were collected immediately before and after exercise at 2, 24, 48, 72 and 96 hours. Established indicators of muscle damage such as maximum isometric torque (MIT), range of motion (ROM), relaxed arm angle (RANG), flexed arm angle (FANG), arm circumference (CIRC), muscle soreness and serum levels of creatine kinase (CK) and lactate dehydrogenase (LDH) were determined at the same time points. Baseline serum levels of Se were also measured. Complementary data regarding assessment of Se status were retrieved by the use of a semi‐quantitative food frequency questionnaire. All measures changed significantly (p
ISSN:0951-6433
1872-8081
DOI:10.1002/biof.5520260301