In vivo photoacoustic imaging of blood vessels with a pulsed laser diode

Photoacoustic imaging is a hybrid imaging modality that is based on the detection of acoustic waves generated by absorption of pulsed light by tissue chromophores such as hemoglobin in blood. For this technique, usually large and costly Q-switched Nd:YAG lasers are used. These lasers provide a pulse...

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Bibliographic Details
Published in:Lasers in medical science 2006-09, Vol.21 (3), p.134-139
Main Authors: Kolkman, Roy G M, Steenbergen, Wiendelt, van Leeuwen, Ton G
Format: Article
Language:English
Subjects:
Acoustics
Blood vessels
Blood Vessels - anatomy & histology
Blood Vessels - diagnostic imaging
Diagnostic Imaging - methods
Humans
Lasers
Low-Level Light Therapy - methods
Medical imaging
Medical technology
Radionuclide Angiography
Spectrum Analysis
Ultrasonic imaging
Ultrasonography
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Summary:Photoacoustic imaging is a hybrid imaging modality that is based on the detection of acoustic waves generated by absorption of pulsed light by tissue chromophores such as hemoglobin in blood. For this technique, usually large and costly Q-switched Nd:YAG lasers are used. These lasers provide a pulse energy of at least several milliJoules. In search of alternative light sources, we investigated the use of a small and compact pulsed laser diode to image blood vessels. We proved that a pulsed laser diode can be applied for imaging blood vessels in vivo.
ISSN:0268-8921
1435-604X
DOI:10.1007/s10103-006-0384-z