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ACE inhibition can improve orthostatic proteinuria associated with nutcracker syndrome

Left renal vein entrapment syndrome (nutcracker syndrome) was documented by magnetic resonance angiography (MRA) as a cause of orthostatic proteinuria in a 14-year-old girl female adolescent. Because of continuous proteinuria we performed a left renal biopsy which showed moderate mesangial hypercell...

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Bibliographic Details
Published in:Pediatric nephrology (Berlin, West) West), 2006-11, Vol.21 (11), p.1765-1768
Main Authors: Ha, Tae-Sun, Lee, Eun-Ju
Format: Article
Language:English
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Summary:Left renal vein entrapment syndrome (nutcracker syndrome) was documented by magnetic resonance angiography (MRA) as a cause of orthostatic proteinuria in a 14-year-old girl female adolescent. Because of continuous proteinuria we performed a left renal biopsy which showed moderate mesangial hypercellularity. Her overt orthostatic proteinuria disappeared after a treatment of angiotensin-converting enzyme (ACE) inhibition. Nutcracker syndrome remains a rare but important cause of elevated protein excretion, which can induce mesangial changes and be improved by ACE inhibitor treatment.
ISSN:0931-041X
1432-198X
DOI:10.1007/s00467-006-0206-3