Importance and Management of Dyslipidemia in the Metabolic Syndrome

The metabolic syndrome is a common disorder characterized by central obesity, impaired glucose tolerance, hypertension, and atherogenic dyslipidemia (including the combination of hypertriglyceridemia, low levels of high-density lipoprotein cholesterol, and a preponderance of small, dense low-density...

Full description

Saved in:
Bibliographic Details
Published in:The American journal of the medical sciences 2005-12, Vol.330 (6), p.295-302
Main Authors: Menuet, Robert, Lavie, Carl J., Milani, Richard V.
Format: Article
Language:English
Subjects:
Anticholesteremic Agents - therapeutic use
Atherosclerosis - etiology
Atherosclerosis - pathology
Atherosclerosis - therapy
Biological and medical sciences
Diet
Drug Combinations
Drug Therapy, Combination
Fish Oils - therapeutic use
General aspects
Humans
Hypertriglyceridemia - complications
Hypertriglyceridemia - pathology
Hypertriglyceridemia - therapy
Life Style
Medical sciences
Metabolic diseases
Miscellaneous
Obesity - complications
Obesity - pathology
Obesity - therapy
Other metabolic disorders
Syndrome
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The metabolic syndrome is a common disorder characterized by central obesity, impaired glucose tolerance, hypertension, and atherogenic dyslipidemia (including the combination of hypertriglyceridemia, low levels of high-density lipoprotein cholesterol, and a preponderance of small, dense low-density lipoprotein particles). In this manuscript, we review the pathogenesis and significance of dyslipidemia in the metabolic syndrome, the role of nonpharmacologic therapy with therapeutic lifestyle changes, and drug therapies, including statins, fibrates, nicotinic acid, and omega-3 fatty acids or fish oils, alone or in drug combinations, to improve lipids and reduce the chance of subsequent cardiovascular disease events.
ISSN:0002-9629
1538-2990
DOI:10.1097/00000441-200512000-00007