Outbreak of Tuberculosis Caused by Mycobacterium caprae in a Zoological Garden

In the autumn of 2004, tuberculosis caused by Mycobacterium caprae occurred in a zoo in Slovenia. A dromedary camel (Camelus dromedarius) was killed after a history of progressive emaciation. Necropsy findings indicated disseminated tuberculosis, which was confirmed by cultivation of M. caprae. Cons...

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Bibliographic Details
Published in:Journal of veterinary medicine. Series B 2006-10, Vol.53 (8), p.387-392
Main Authors: Pate, M, Švara, T, Gombač, M, Paller, T, Žolnir-Dovč, M, Emeršič, I, Prodinger, W.M, Bartoš, M, Zdovc, I, Krt, B, Pavlik, I, Cvetnić, Ž, Pogačnik, M, Ocepek, M
Format: Article
Language:English
Subjects:
animal diseases
animal pathogenic bacteria
Animals
Animals, Zoo - microbiology
Bacteria
bison
Bison - microbiology
Camelus - microbiology
disease diagnosis
disease outbreaks
Disease Outbreaks - veterinary
disease transmission
dromedaries
Epidemiology
Female
Genotype
Male
Mammals
Mycobacterium - classification
Mycobacterium - isolation & purification
Mycobacterium bovis subsp. caprae
Mycobacterium Infections - epidemiology
Mycobacterium Infections - pathology
Mycobacterium Infections - transmission
Mycobacterium Infections - veterinary
pathogen identification
Phylogeny
Slovenia - epidemiology
Tuberculosis
Tuberculosis - epidemiology
Tuberculosis - pathology
Tuberculosis - transmission
Tuberculosis - veterinary
zoo animals
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Summary:In the autumn of 2004, tuberculosis caused by Mycobacterium caprae occurred in a zoo in Slovenia. A dromedary camel (Camelus dromedarius) was killed after a history of progressive emaciation. Necropsy findings indicated disseminated tuberculosis, which was confirmed by cultivation of M. caprae. Consequently, a tuberculin skin test was performed in all epidemiologically linked animals and another dromedary camel and six bison (Bison bison) were positive and killed. Mycobacterium caprae was isolated from two bison while M. scrofulaceum and Mycobacterium spp. were found in two other bison, respectively. The second dromedary camel was found to be negative for mycobacteria under both microscopic and culture tests. The isolates were investigated with commercial identification kits, IS6110 PCR, IS6110 restriction fragment length polymorphism analysis, spoligotyping and mycobacterial interspersed repetitive units typing. Genotyping results revealed that the dromedary camel and the two bison were infected by the same M. caprae.
ISSN:0931-1793
1863-1959
1439-0450
1863-2378
DOI:10.1111/j.1439-0450.2006.01000.x